Evidence map›Paper›PMID 41626087›Full record

ArticleClinical case reports2026

Photobiomodulation and Radio-Epithelitis in Anal Carcinoma: A Case-Report and Clinical Reflection on Emerging Preventive and Supportive Care Modalities.

Michèle Pelletier-Aouizerate, Yvona Zivic

Abstract read
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michèle Pelletier-AouizerateEuropean LED Academy Toulon France.ORCID https://orcid.org/0000-0002-0231-9053
Yvona ZivicUniversity of South Wales London UK.ORCID https://orcid.org/0000-0002-7044-1333

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radio-induced dermatitis, a frequent adverse effect of radiation therapy, is particularly prevalent in patients treated for anal margin carcinoma. It may present with varying severity, causing significant pain and impairment of daily mobility, influenced by both patient-related factors and treatment regimens. The standard management is challenging, largely topical and supportive, often insufficient to adequately address morbidity in severe or refractory cases. Photobiomodulation therapy using red-light and near-infrared light has been increasingly recognized in oncology supportive care; however, evidence remains limited for perianal radiation-induced skin toxicity and use prior to re-irradiation. We report the case of a 79-year-old woman treated for epidermoid carcinoma of the anal margin who developed grade 2 radiation-induced epithelitis during chemoradiotherapy, refractory to conventional topical treatments. Red-light photobiomodulation therapy (RL-PBMT, 632 nm, 67 mW/cm

Indexed as

burns preventionepigeneticoncodermatologypre‐conditioningradiation‐induced dermatitisradio‐epithelitisradiotherapy side‐effectsred‐light therapysupportive cancer care

Identifiers

PMID41626087
PMCPMC12856218

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.