ArticleJournal of surgical case reports2026
Familial adult-onset chronic idiopathic megacolon: diagnostic and surgical challenges-a case report.
Article in Journal of surgical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Chronic idiopathic megacolon is a rare disorder characterized by persistent colonic dilatation without obstruction or secondary causes. It is usually diagnosed in childhood, often linked to Hirschsprung's disease; adult-onset cases are exceedingly rare, especially with familial predisposition. We report a man in his 30s with progressive abdominal distension, prior adolescent colectomy, and family history suggesting genetic susceptibility. After excluding secondary causes, chronic idiopathic megacolon was diagnosed. Conservative management failed, necessitating subtotal colectomy with ileorectal anastomosis, leading to complete symptom resolution. Histopathology confirmed normal ganglion cells. Adult-onset idiopathic megacolon poses diagnostic and therapeutic challenges and may have a genetic basis. Subtotal colectomy is safe and effective in refractory cases.
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