ArticleCureus2025
Pancreatic Head Cancer and Intrahepatic Cholangiocarcinoma Occurring After Surgery for Congenital Biliary Dilatation Associated With Pancreaticobiliary Maljunction: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Congenital biliary dilatation (CBD), frequently associated with pancreaticobiliary maljunction (PBM), predisposes patients to biliary tract malignancies due to chronic reflux of pancreatic juice into the biliary epithelium. Although biliary diversion reduces carcinogenic risk, malignancy may still arise many years after surgery. A 69-year-old woman underwent choledochal cyst excision and Roux-en-Y hepaticojejunostomy at age 52. Seventeen years later, she developed pancreatic head adenocarcinoma, treated with subtotal stomach-preserving pancreaticoduodenectomy (SSPPD) while preserving and reusing the original Roux limb. Six months later, she developed intrahepatic cholangiocarcinoma, requiring an extended right hepatectomy with reconstruction using the same preserved Roux limb. She remains disease-free 18 months after surgery. Patients with CBD and PBM remain at lifelong risk of malignancy, especially when surgery is performed in adulthood. Reuse of a preserved Roux limb is a feasible and effective strategy in complex reoperations.
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