Evidence map›Paper›PMID 41625869›Full record

ReviewCureus2025

Uterine Transplantation for Absolute Uterine Factor Infertility: From Bench to Bedside.

Jesus Alberto Sanson-Riofrio, Ismael Brito-Toledo, Angelica Morelia, Alvar J Vacio Olguin, David Rayas Ruiz, Maria Del Rosario Garcia, Roberto D Robles, Soledad Ruiz-Matus, Patricia Goldstein, Manuel M Meraz

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jesus Alberto Sanson-RiofrioSurgical Oncology, Mexican Institute of Social Security, Mexico City, MEX.
Ismael Brito-ToledoColon and Rectal Tumors, Oncology Hospital, National Medical Center Century XXI, Mexico City, MEX.
Angelica MoreliaEpidemiology, Hospital General de Zona No. 33, Mexican Institute of Social Security, Mexico City, MEX.
Alvar J Vacio OlguinSurgical Oncology, Oncology Hospital, Centro Médico Nacional Siglo XXI, Mexico City, MEX.
David Rayas RuizSurgical Oncology, Mexican Institute of Social Security, Mexico City, MEX.
Maria Del Rosario GarciaIntensive Care, Mexican Institute of Social Security, Mexico City, MEX.
Roberto D RoblesSurgical Oncology, Mexican Institute of Social Security, Mexico City, MEX.
Soledad Ruiz-MatusPhysics, National Autonomus University of Mexico, Mexico City, MEX.
Patricia GoldsteinPhysics, Facultad de Ciencias Universidad Nacional Autonoma de Mexico, Mexico City, MEX.
Manuel M MerazPostgraduate Studies and Research, Medicine, Escuela Superior de Medicina - Instituto Politécnico Nacional (ESM IPN), Mexico City, MEX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uterus transplantation (UTx) has emerged as a promising reproductive option for women with absolute uterine factor infertility, and this narrative review offers an integrated translational overview of its progression from experimental research to clinical practice based on a structured qualitative synthesis of the literature retrieved from PubMed/MEDLINE, Embase, and Scopus between 2000 and June 2025, including original studies, reviews, case reports, meta-analyses, and clinical guidelines while excluding grey literature, incomplete abstracts, and non-human studies. Without performing quantitative synthesis or meta-analysis, the review highlights key historical milestones, advances in microsurgical technique and vascular preservation, evolving immunosuppressive strategies, reported graft function, reproductive and neonatal outcomes, and ethical considerations related to donor safety and equitable access. The review also notes that more than 90 uterine transplant procedures worldwide have led to over 50 reported live births, thereby demonstrating growing clinical reliability, while underscoring persistent challenges, such as graft rejection, infectious risk, and the long-term effects of immunosuppression, as the field continues to mature toward broader clinical applicability.

Indexed as

absolute uterine factor infertility (aufi)assisted reproductionpregnancyreproductive medicineuterus transplantation

Identifiers

PMID41625869
PMCPMC12856687

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.