ArticleCureus2025
Admission Day and Outcomes in Myocardial Infarction With Cardiogenic Shock: A Nationwide Propensity Score-Matched Study.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Diurnal Variation in Mechanical Circulatory Support Initiation and Associated Outcomes.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe "weekend effect" refers to potential disparities in clinical outcomes based on the timing of hospital admission, with prior studies offering conflicting results, particularly in patients with acute myocardial infarction (AMI) complicated by cardiogenic shock (CS). This study evaluates the impact of admission timing on outcomes in patients with ST-elevation myocardial infarction and CS (STEMI-CS) and patients with non-STEMI and CS (NSTEMI-CS).
methodsWe conducted a retrospective analysis using the Nationwide Inpatient Sample from 2016 to 2021. Patients with STEMI-CS and NSTEMI-CS were identified using ICD-10 (International Classification of Diseases, Tenth Revision) codes and stratified by weekday versus weekend admissions. Propensity score matching and multivariable logistic regression were employed to adjust for confounders. The primary outcome was in-hospital mortality; secondary outcomes included acute stroke, pacemaker implantation, and resource utilization.
resultsAmong 14,060 propensity-matched STEMI-CS patients (7,030 weekday and 7,030 weekend admissions), in-hospital mortality was higher in weekday compared to weekend admissions (2,373 (33.8%) vs. 2,261 (32.2%), p=0.044). Pacemaker implantation was less frequent in weekday admissions (28 (0.4%) vs. 55 (0.8%), p=0.003). Other outcomes, including percutaneous coronary intervention, acute stroke, sudden cardiac arrest, sepsis, pulmonary embolism, arrhythmias, and device implantation, were comparable between groups. Among 9,490 propensity-matched NSTEMI-CS patients (4,745 weekday and 4,745 weekend admissions), weekend admissions were associated with higher in-hospital mortality compared to weekdays (1,485 (31.3%) vs. 1,372 (28.9%), p=0.011), while other outcomes remained similar between groups.
conclusionAdmission timing influences in-hospital mortality in patients with CS secondary to AMI, with contrasting trends observed between STEMI-CS and NSTEMI-CS cohorts. These findings suggest that variations in hospital protocols, staffing, or resource availability may contribute to these differences. Further research is warranted to elucidate the underlying mechanisms and develop strategies to optimize care delivery across all admission times.
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