ArticleCureus2025
Intraoperative Incidence of Bacteremia During Surgical Management of Non-tubercular Spondylodiscitis: A Prospective Analysis.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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11 authors.
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Abstract
Introduction Non-tubercular spondylodiscitis is a serious spinal infection that can lead to significant morbidity. The potential for bacteremia during surgical manipulation of infected disc material has not been well studied. This prospective study aimed to evaluate the incidence of bacteremia during the surgical procedure in patients with non-tubercular spondylodiscitis. Methods A single-center, prospective study was conducted from August 2019 to May 2020, enrolling 28 consecutive patients with biopsy-proven or MRI-suspected non-tuberculous vertebral osteomyelitis who underwent surgery. Preoperative blood, urine, and throat swab cultures were performed after a 48-hour antibiotic-free interval for patients who had been on prior antibiotics. Intraoperative venous blood cultures were collected immediately after disc preparation but before antibiotic administration. Surgical procedures included cervical discectomy/corpectomy, thoracic laminectomy with fixation, and lumbar Transforaminal Lumbar Interbody Fusion (TLIF). Culture results from blood, disc material, and other samples were analyzed. Results Intraoperative blood culture was positive in three patients (12.5%), with one patient showing the same organism preoperatively. Five patients had growth in disc material cultures; only one matched preoperative and perioperative blood cultures with methicillin-resistant
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