Evidence map›Paper›PMID 41625722›Full record

ArticleJournal of cardiovascular echography

Correlation of Serum Tumor Marker Carbohydrate Antigen 125 with Ankle-Brachial Index in Patients with Coronary Artery Disease.

Ibrahim Mohamed Elsayed Eltahan, Amany R M Serag, Mohamed Y Abd El Khalek, Hend M Abdou

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In one paragraph

Article in Journal of cardiovascular echography. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ibrahim Mohamed Elsayed EltahanDepartment of Cardiology, Faculty of Medicine, Menoufia University, Menoufia, Egypt.
Amany R M SeragDepartment of Cardiology, Faculty of Medicine, Menoufia University, Menoufia, Egypt.
Mohamed Y Abd El KhalekDepartment of Cardiology, Faculty of Medicine, Menoufia University, Menoufia, Egypt.
Hend M AbdouDepartment of Cardiology, Faculty of Medicine, Menoufia University, Menoufia, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Peripheral arterial disease shares common pathophysiological mechanisms with coronary artery disease (CAD), including inflammation and atherosclerosis. Carbohydrate antigen 125 (CA-125), previously known as a tumor marker, has been suggested to be elevated in patients with heart failure and CAD. Aim: The aim of this study was to assess the correlation of serum tumor marker carbohydrate antigen 125 with ankle-brachial index (ABI) in patients with CAD. Materials and Methods: A prospective study was conducted on 60 CAD patients. Based on ABI, they were grouped into low ABI (≤0.9) and normal ABI (1-1.4). Serum CA-125 and high-sensitivity C-reactive protein (hs-CRP) were measured, and transthoracic echocardiographic parameters were evaluated. Results: CA-125 was significantly higher in patients with low ABI compared to those with normal ABI (13.17 ± 4.48 vs. 10.03 ± 3.18 U/ml, Conclusion: Serum CA-125 is a readily available biomarker that may have utility as a supplementary indicator of atherosclerotic burden and vascular risk in patients with CAD.

Indexed as

Ankle–brachial indexcarbohydrate antigen 125coronary artery diseaseperipheral arterial disease

Identifiers

PMID41625722
PMCPMC12857789

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.