Evidence map›Paper›PMID 41625440›Full record

ArticleSynthetic and systems biotechnology2026

Modifying the upstream open reading frames of cellulase gene enhances cellulase production in

Shuai Zhao, Xin Shen, Ting-Yu Zhou, Yan-Hao Zhao, Di Tian, Xue-Mei Luo, Zhi-Peng Zhou, Xin-Qing Zhao, Jia-Xun Feng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Synthetic and systems biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shuai ZhaoState Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangxi Technology Innovation Center for Microbial Resources Development and Utilization, College of Life Science and Technology, Guangxi University, Nanning, 530004, China.
Xin ShenState Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangxi Technology Innovation Center for Microbial Resources Development and Utilization, College of Life Science and Technology, Guangxi University, Nanning, 530004, China.
Ting-Yu ZhouState Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangxi Technology Innovation Center for Microbial Resources Development and Utilization, College of Life Science and Technology, Guangxi University, Nanning, 530004, China.
Yan-Hao ZhaoState Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangxi Technology Innovation Center for Microbial Resources Development and Utilization, College of Life Science and Technology, Guangxi University, Nanning, 530004, China.
Di TianState Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangxi Technology Innovation Center for Microbial Resources Development and Utilization, College of Life Science and Technology, Guangxi University, Nanning, 530004, China.
Xue-Mei LuoState Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangxi Technology Innovation Center for Microbial Resources Development and Utilization, College of Life Science and Technology, Guangxi University, Nanning, 530004, China.
Zhi-Peng ZhouNational Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China.
Xin-Qing ZhaoNational Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Jia-Xun FengState Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangxi Technology Innovation Center for Microbial Resources Development and Utilization, College of Life Science and Technology, Guangxi University, Nanning, 530004, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cellulase plays an irreplaceable role in biomanufacturing using plant biomass as feedstock. However, improving cellulase production by fungi through manipulation of upstream open reading frames (uORFs) in the 5'-untranslated regions (5'-UTR) of cellulase genes has been less frequently explored. This study aimed to screen uORFs in the 5'-UTR of cellulase genes in

Indexed as

Endo-β-1,4-glucanaseGene editingPenicillium oxalicumuORF

Identifiers

PMID41625440
PMCPMC12855567

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.