Evidence map›Paper›PMID 41625323›Full record

ArticleFuture healthcare journal2026

Demographic and regional disparities in cancer cachexia-related mortality in the USA from 1999 to 2020 - A retrospective cross-sectional study.

Zahra Quettawala Mufaddal, Rafay Khan, Omer Mustafa Siddiqui, Shanza Malik, Alina Baig, Mohammad Arham Siddiq, Syed Husain Farhan, Roha Saeed Memon, Ishaque Hameed, Christopher J Haas and 1 more

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Article in Future healthcare journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Zahra Quettawala MufaddalDepartment of Medicine, Dow University of Health Science, Karachi, Pakistan.
Rafay KhanDepartment of Medicine, Dow University of Health Science, Karachi, Pakistan.
Omer Mustafa SiddiquiDepartment of Medicine, Dow University of Health Science, Karachi, Pakistan.
Shanza MalikDepartment of Medicine, Dow University of Health Science, Karachi, Pakistan.
Alina BaigDepartment of Pathology, Sullivan Nicolaides, Springfield Lakes, Queensland, Australia.
Mohammad Arham SiddiqDepartment of Medicine, Jinnah Sindh Medical University, Karachi, Pakistan.
Syed Husain FarhanDepartment of Medicine, Dow University of Health Science, Karachi, Pakistan.
Roha Saeed MemonDepartment of Medicine, Jacobi Medical Center-NYCHHC/Albert Einstein College of Medicine, Bronx, New York, USA.
Ishaque HameedDepartment of Medicine, Medstar Health, Baltimore, Maryland, USA.
Christopher J HaasDepartment of Medicine, Medstar Health, Baltimore, Maryland, USA.
Anita TammaraDepartment of Medicine, Medstar Health, Baltimore, Maryland, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Nearly 2 million new cancer cases and over half a million cancer deaths in the USA were reported in 2024. Still there remains a paucity of data on cancer-cachexia-related mortality. Methods: The Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER) database was utilised to identify cases where both cachexia and cancer were listed as either contributory or underlying causes of death between 1999 and 2020. Results: Between 1999 and 2020, there were 64,106 deaths related to cancer and cachexia among adults aged ≥55 years. Overall, a declining trend has been identified from 1999 to 2019. Black patients had 1.4 times higher mortality than White patients. Rural dwellers had higher mortality than urban adults. Lastly, states with age-adjusted mortality rates (AAMR) in the 90th percentile (California, South Carolina, Utah, Georgia, Alaska and New Hampshire) displayed approximately five-fold higher AAMR than states in the bottom 10th percentile. Conclusion: Tailored public health strategies for healthcare access and risk factor management are needed to address these disparities.

Indexed as

CachexiaCancer outcomesFuture health policiesPublic healthRacial disparitiesTrends in mortality

Identifiers

PMID41625323
PMCPMC12854984

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.