ReviewFood science & nutrition2026
Nutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights.
Review in Food science & nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Nutritional and Phytochemical Characterization of Commercially Available Chia, Quinoa, Pumpkin Seed, Flaxseed and Triticale Products.Plants (Basel, Switzerland) · 2026Article
- Nutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights.Food science & nutrition · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Edible seeds have gained substantial scientific attention for their exceptional nutrient density and potential health-promoting properties. They are rich in dietary fiber, high-quality proteins, mono- and polyunsaturated fatty acids, omega-3 fatty acids, vitamins (E, C, and K), and minerals such as magnesium, zinc, potassium, and iron. Bioactive compounds like polyphenols, carotenoids, and peptides contribute to their strong antioxidant and anti-inflammatory effects, helping to mitigate oxidative stress and inflammation linked to chronic diseases. This review focuses on pumpkin, flax, sesame, chia, and melon seeds, valuable sources of essential micronutrients and bioactives with demonstrated nutraceutical potential. Pumpkin seeds enhance immune strength because of their mineral profile, whereas chia seeds provide omega-3 fatty acids associated with neuroprotection and anti-Alzheimer's effects. The omega-3 content of flax and chia seeds offers cardioprotective benefits, whereas sesame lignans (sesamin) exhibit lipid-lowering and anti-aging properties. Flaxseed's secoisolariciresinol diglycoside (SDG) contributes to cardiovascular and anti-cancer effects, and melon seed squalene supports immune health and exerts anti-cancer activity. Mechanistic studies highlight these seeds' ability to regulate molecular pathways related to oxidative stress, inflammation, hypertension, diabetes, cancer, and metabolic disorders. Their bioactive constituents act through antioxidant, anti-inflammatory, and metabolic-regulating mechanisms, validating their classification as functional foods. Evidence from clinical and biochemical studies largely supports these benefits, although some claims stem from preliminary or in vitro findings. Overall, pumpkin, flax, sesame, chia, and melon seeds demonstrate significant potential as natural sources of nutrients and bioactive compounds that promote cardiovascular, metabolic, and immune health. Their integration into daily diets and functional food formulations could play a vital role in preventing lifestyle-related chronic diseases and enhancing overall well-being.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.