ArticleFrontiers in endocrinology2025
Resistance training as a key strategy for high-quality weight loss in men and women.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Increasing skeletal muscle mass and strength during incretin-based weight loss.Obesity pillars · 2026Article
- Review
- Combined exercise for body composition and cardiometabolic health in obese young people meta analysis.iScience · 2026Article
- Weight maintenance after discontinuation of GLP-1 therapies.EClinicalMedicine · 2026Review
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3 authors.
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Abstract
Background: Preserving fat-free mass (FFM) during weight loss is critical for preventing sarcopenia and maintaining metabolic health. This study examined the effects of resistance training (RT), aerobic exercise (AR), and no exercise (NO) on body composition during a calorie-restricted diet. Methods: This retrospective cohort study included 304 adults (183 men, 121 women; aged 20-74 years; BMI: 18.5-45 kg/m Results: Mean follow-up was 5.1 months ± 0.42 months. In men, total weight loss was similar across groups (NO: - 8.5 kg ± 3.2 kg; AR: - 9.0 kg ± 4.2 kg; RT: - 7.7 kg ± 4.2 kg). However, RT produced the greatest reduction in fat mass (RT: - 8.9 kg ± 4.1 kg; AR: - 7.8 kg ± 3.2 kg; NO: - 5.8 kg ± 2.5 kg) and was the only modality associated with an increase in fat-free mass (RT: + 0.8 kg ± 5.0 kg vs. AR: - 1.1 kg ± 2.0 kg and NO: - 2.8 kg ± 1.4 kg). ABC declined in all groups, with larger reductions in RT (- 9.0 cm ± 3.7 cm) and AR (- 8.0 cm ± 3.2 cm) compared with NO (- 6.1 cm ± 2.4 cm). Among women, weight loss was also comparable between groups (NO: - 7.13 kg ± 3.27 kg; AR: - 6.43 kg ± 3.53 kg; RT: - 5.42 kg ± 3.76 kg). RT produced the greatest fat-mass reduction (RT: - 6.36 kg ± 3.82 kg; NO: - 5.47 kg ± 2.64 kg; AR: - 4.10 kg ± 3.17 kg) and was the only modality that increased fat-free mass (RT: + 0.90 kg ± 1.24 kg). Both NO (- 2.94 kg ± 1.40 kg) and AR (- 0.37 kg ± 1.45 kg) experienced FFM loss. The fat mass (FM)-to-weight loss ratio was lowest in the NO group (0.7 ± 0.2), higher in AR (0.86 ± 0.2), and highest in RT (1.1 ± 0.7; Conclusion: RT enhances weight-loss quality by maximizing FM reduction while preserving or increasing FFM. Incorporating RT into weight-loss programs may improve long-term weight maintenance and mitigate FFM loss.
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