Evidence map›Paper›PMID 41625150›Full record

ArticleFrontiers in cellular and infection microbiology2025

Ocular surface microbiota alterations in patients with pterygium.

Yiyuan Guo, Gege Tian, Guangzhong Feng, Yong Li, Biying Wang, Jiaxin Wang, Hong Zhang, Yongsheng Hou

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yiyuan Guo *Department of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Gege Tian *Department of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Guangzhong FengDepartment of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Yong LiCollege of Arts and Sciences, Northeast Agricultural University, Harbin, China.
Biying WangDepartment of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Jiaxin WangDepartment of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Hong ZhangDepartment of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Yongsheng HouDepartment of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To examine the alterations in the ocular surface microbiota and microbial diversity in patients with pterygium after different durations of electronic device use. Methods: This study involved 31 individuals diagnosed with unilateral pterygium. Conjunctival sac swabs were collected from both eyes, and 16S rRNA sequencing was used to identify the species and quantity of bacteria. The microbial composition was annotated and represented through comprehensive bioinformatics analysis. Results: The alpha diversity did not differ significantly between the eyes with pterygium and the contralateral eyes. The Chao1 and Shannon indices for the eyes with pterygium of the patients who used electronic devices for extended periods were significantly higher than those for their contralateral eyes. Principal coordinate analysis revealed that the beta diversity of the eyes with pterygium was similar to that of the contralateral eyes. Genus-level differential analysis revealed that the relative abundance of Conclusion: The ocular surface of eyes with pterygium had increased colonization by opportunistic pathogenic bacteria. Excessive exposure to blue light, which may result from prolonged use of electronic devices, may be a risk factor for the development of pterygium.

Indexed as

BacteriaEyeMicrobiotaPterygiumAdultAgedComputational BiologyConjunctivaDNA, BacterialDNA, RibosomalFemaleHumansMaleMiddle AgedRNA, Ribosomal, 16SSequence Analysis, DNADNA, BacterialDNA, RibosomalRNA, Ribosomal, 16S16S rRNA sequencingmicrobial communityocular surface microbiotapathogenesispterygium

Identifiers

PMID41625150
PMCPMC12855565

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.