Evidence map›Paper›PMID 41625138›Full record

ArticleSAGE open medical case reports2026

A case report on nebulized human umbilical cord mesenchymal stem cell-derived exosome therapy for asthma and chronic obstructive pulmonary disease: A preliminary clinical evaluation.

Basmullah Yusof, Rui Qing Foo, Manickam Ravichandran, Mohammad Auwal Sa'ad, Seng Kong Tham

Abstract readCase Reports
In one paragraph

Article in SAGE open medical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Basmullah YusofALPS Medical Centre, ALPS Global Holding Berhad, Kuala Lumpur, Malaysia.
Rui Qing FooCelestialab Sdn Bhd, ALPS Global Holding Berhad, Kuala Lumpur, Malaysia.
Manickam RavichandranMygenome, ALPS Global Holding Berhad, Kuala Lumpur, Malaysia.
Mohammad Auwal Sa'adCelestialab Sdn Bhd, ALPS Global Holding Berhad, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0009-0008-1672-7358
Seng Kong ThamALPS Global Holding Berhad, Kuala Lumpur, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human umbilical cord mesenchymal stem cell-derived exosomes have gained attention as a promising, cell-free regenerative therapy due to their immunomodulatory and tissue-repair properties. This study retrospectively evaluated the safety and efficacy of nebulized human umbilical cord mesenchymal stem cell exosome therapy in three patients with asthma and/or chronic obstructive pulmonary disease who underwent weekly nebulized exosome therapy for 5 weeks at ALPS Medical Centre, Kuala Lumpur, Malaysia. Clinical outcomes were assessed using pulmonary function tests, inflammatory markers, and laboratory parameters. Post-therapy, pulmonary function improved, with increases in forced expiratory volume in 1 s from 2.59 to 3.4 L (

Indexed as

asthmaCOPDhUCMSC exosomesnebulized therapypulmonary functionregenerative medicine

Identifiers

PMID41625138
PMCPMC12855734

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.