ReviewCureus2026
Effectiveness of the Non-restorative Cavity Control (NRCC) Approach in Managing Dentinal Caries in Primary Teeth: A Systematic Review.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early childhood caries (ECC) is a highly prevalent, transmissible, and infectious disease affecting 60-90% of children worldwide. Conventional restorative therapy has traditionally been the mainstay of ECC management, but it often shows unfavorable outcomes in pediatric populations. Recently, there has been a shift toward minimally invasive interventions or non-restorative cavity control (NRCC). This review evaluated the effectiveness of NRCC in managing dentinal caries in primary teeth. A comprehensive search was conducted in Scopus, PubMed, MEDLINE, and Web of Science using keywords related to NRCC and primary dentition. Inclusion criteria were peer-reviewed randomized clinical trials (RCTs) published from 2015 to 2025, involving children ≤12 years with active dentinal lesions scored using the International Caries Detection and Assessment System (ICDAS) form 3 to 6. Studies were assessed for quality and risk of bias using the Cochrane Risk of Bias 2 (ROB-2) tool. Nine RCTs were finally included in the review. Most studies demonstrated that 38% silver diamine fluoride (SDF) effectively arrested dentinal caries, even with minimal application (30 seconds). One study reported that restorative techniques, such as the Hall technique, had higher survival rates than SDF. Nevertheless, SDF was well accepted by children and parents, who reported high satisfaction. Current evidence supports NRCC over conventional restorative therapy for managing dentinal caries in primary teeth. Despite aesthetic concerns, SDF remains an effective, safe, feasible, and well-accepted option for children and parents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.