Evidence map›Paper›PMID 41624894›Full record

ArticleFrontiers in immunology2025

SARS-CoV-2 spike antibodies cross-react with dengue virus and enhance infection

Kamini Jakhar, Sudipta Sonar, Gagandeep Singh, Tejeswara Rao Asuru, Garima Joshi, Nisha Beniwal, Tania Sarkar, Mahima Tiwari, Jaskaran Kaur, Deepak Kumar Rathore and 19 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Kamini Jakhar *Centre for Virus Research, Therapeutics and Vaccines, Translational Health Science and Technology Institute, Faridabad, India.
Sudipta Sonar *Centre for Virus Research, Therapeutics and Vaccines, Translational Health Science and Technology Institute, Faridabad, India.
Gagandeep SinghComputational Biophysics and Computer-Aided Drug Design (CADD) Group, Computational and Mathematical Biology Centre (CMBC), Translational Health Science and Technology Institute (THSTI), Faridabad, India.
Tejeswara Rao Asuru *Molecular Medicine, Regional Centre for Biotechnology, Faridabad, India.
Garima Joshi *Molecular Medicine, Regional Centre for Biotechnology, Faridabad, India.
Nisha BeniwalCentre for Virus Research, Therapeutics and Vaccines, Translational Health Science and Technology Institute, Faridabad, India.
Tania SarkarCentre for Virus Research, Therapeutics and Vaccines, Translational Health Science and Technology Institute, Faridabad, India.
Mahima TiwariCentre for Virus Research, Therapeutics and Vaccines, Translational Health Science and Technology Institute, Faridabad, India.
Jaskaran KaurCentre for Virus Research, Therapeutics and Vaccines, Translational Health Science and Technology Institute, Faridabad, India.
Deepak Kumar RathoreCentre for Immunobiology and Immunotherapy, Translational Health Science and Technology Institute, Faridabad, India.
Banwari LalCentre for Virus Research, Therapeutics and Vaccines, Translational Health Science and Technology Institute, Faridabad, India.
Sandeep KumarCentre for Virus Research, Therapeutics and Vaccines, Translational Health Science and Technology Institute, Faridabad, India.
Puneet SrivastavCentre for Virus Research, Therapeutics and Vaccines, Translational Health Science and Technology Institute, Faridabad, India.
Satendra KumarCentre for Virus Research, Therapeutics and Vaccines, Translational Health Science and Technology Institute, Faridabad, India.
Vikas PhagnaCentre for Virus Research, Therapeutics and Vaccines, Translational Health Science and Technology Institute, Faridabad, India.
Sushma MithinaCentre for Virus Research, Therapeutics and Vaccines, Translational Health Science and Technology Institute, Faridabad, India.
Lokesh KumarCentre for Virus Research, Therapeutics and Vaccines, Translational Health Science and Technology Institute, Faridabad, India.
Vishal GuptaCentre for Virus Research, Therapeutics and Vaccines, Translational Health Science and Technology Institute, Faridabad, India.
Pallavi KshetrapalCentre for Maternal and Child Health, Translational Health Science and Technology Institute, Faridabad, India.
Savita SinghCentre for Maternal and Child Health, Translational Health Science and Technology Institute, Faridabad, India.
Nitya WadhwaCentre for Maternal and Child Health, Translational Health Science and Technology Institute, Faridabad, India.
Ramachandran ThiruvengadamCentre for Maternal and Child Health, Translational Health Science and Technology Institute, Faridabad, India.
Sreevatsan RaghavanCentre for Maternal and Child Health, Translational Health Science and Technology Institute, Faridabad, India.
Mudita GosainCentre for Maternal and Child Health, Translational Health Science and Technology Institute, Faridabad, India.
Tripti ShrivastavaCentre for Virus Research, Therapeutics and Vaccines, Translational Health Science and Technology Institute, Faridabad, India.
Sankar BhattacharyyaCentre for Virus Research, Therapeutics and Vaccines, Translational Health Science and Technology Institute, Faridabad, India.
Shailendra AsthanaComputational Biophysics and Computer-Aided Drug Design (CADD) Group, Computational and Mathematical Biology Centre (CMBC), Translational Health Science and Technology Institute (THSTI), Faridabad, India.
Prasenjit GuchhaitMolecular Medicine, Regional Centre for Biotechnology, Faridabad, India.
Shailendra ManiCentre for Virus Research, Therapeutics and Vaccines, Translational Health Science and Technology Institute, Faridabad, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presence of non-neutralizing antibodies of any dengue serotype increases the severity of subsequent infection by other dengue serotypes. During the SARS-CoV-2 pandemic, the number of symptomatic dengue cases increased in India. We found that antibodies isolated from convalescent plasma from COVID-19 patients enhances DENV2 infection

Indexed as

Antibodies, ViralCOVID-19DengueDengue VirusSARS-CoV-2Spike Glycoprotein, CoronavirusAnimalsAntibodies, NeutralizingAntibody-Dependent EnhancementCross ReactionsDisease Models, AnimalFemaleHumansMiceAntibodies, NeutralizingAntibodies, ViralSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2AG129 mice modelantibody-dependent enhancementcross-reactivitydengue virusSARS-CoV-2

Identifiers

PMID41624894
PMCPMC12852381

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.