Evidence map›Paper›PMID 41624815›Full record

ArticleFrontiers in pediatrics2025

Case Report: Glucose transporter 1 deficiency syndrome misdiagnosed as bacterial meningitis.

Man Wang, Cuijin Wang, Li Shang, Yamei Feng, Dandan Huang, Qin Li, Jiwen Wang, Hui Guo, Yingyan Wang

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Man Wang *Epilepsy Center, Shanghai Deji Hospital, Qingdao University, Shanghai, China.
Cuijin Wang *Department of Neurology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Li Shang *Epilepsy Center, Shanghai Deji Hospital, Qingdao University, Shanghai, China.
Yamei FengEpilepsy Center, Shanghai Deji Hospital, Qingdao University, Shanghai, China.
Dandan HuangEpilepsy Center, Shanghai Deji Hospital, Qingdao University, Shanghai, China.
Qin LiEpilepsy Center, Shanghai Deji Hospital, Qingdao University, Shanghai, China.
Jiwen WangDepartment of Neurology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hui GuoEpilepsy Center, Shanghai Deji Hospital, Qingdao University, Shanghai, China.
Yingyan WangDepartment of Neurology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Glucose transporter 1 deficiency syndrome (Glut1DS), caused by Method: Retrospective analysis of two patients with Glut1DS admitted to our hospital between July 2023 and July 2025. Clinical features, cerebrospinal fluid (CSF) profiles, genetic testing, and responses to ketogenic diet (KD) were evaluated. Both cases were preliminarily diagnosed with bacterial meningitis in local hospitals based on low CSF glucose levels. Results: Case 1: A 15-day-old male infant with fever and lethargy had persistently low CSF glucose (1.2-1.64 mmol/L; CSF/blood glucose ratio: 0.22-0.32). He was diagnosed as atypical bacterial meningitis and underwent empirical antibiotic therapy lasting over 30 days. Genetic testing confirmed Conclusion: low CSF glucose is a critical diagnostic clue for Glut1DS, not exclusive to CNS infections. In infants with seizures, developmental delays, or motor dysfunction, CSF analysis and targeted

Indexed as

bacterial meningitisglucose transporter 1 deficiency syndromeinfantketogenic dietSLC2A1

Identifiers

PMID41624815
PMCPMC12852347

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