Evidence map›Paper›PMID 41624802›Full record

ArticleGastroenterology & hepatology2025

Natural Products for the Treatment of Irritable Bowel Syndrome.

Sophie Brigstocke, Darren M Brenner

Abstract read
In one paragraph

Article in Gastroenterology & hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sophie BrigstockeDivision of Gastroenterology and Hepatology, Department of Medicine, Northwestern University, Chicago, Illinois.
Darren M BrennerDivision of Gastroenterology and Hepatology, Department of Medicine, Northwestern University, Chicago, Illinois.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Irritable bowel syndrome (IBS) is a common disorder of gut-brain interaction that significantly impacts quality of life. Studies indicate that more than one-third of patients with IBS use nonphar-macologic therapies, which include natural products and mind-body therapies, with higher prevalence identified among women, younger individuals, and those with higher education levels. This article examines the efficacy and safety of various natural products for the treatment of IBS, including fiber supplements, probiotics, herbal remedies (including Aloe vera and peppermint oil), and dietary supplements. Although some therapies show promise in symptom management, the evidence remains mixed for many of these interventions. Further high-quality research is needed to establish the role of many of these therapies in IBS treatment.

Indexed as

dietfiberherbal supplementsIrritable bowel syndromenatural products

Identifiers

PMID41624802
PMCPMC12853684

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.