Evidence map›Paper›PMID 41624726›Full record

ArticleACS physical chemistry Au2026

Proton Nuclear Magnetic Resonance Relaxation in Aqueous Sugar Solutions: Can Low-Field Nuclear Magnetic Resonance Relaxation Measurements Differentiate between "Bound" and "Free" Water?

Vasantha Gowda, Ivan Argatov, Olle Söderman, Vitaly Kocherbitov

Abstract read
In one paragraph

Article in ACS physical chemistry Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Irradiation-induced modulation of TRadiological physics and technology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vasantha GowdaDepartment of Biomedical Science, Faculty of Health and Society, Malmö University, Malmö SE-205 06, Sweden.
Ivan ArgatovDepartment of Biomedical Science, Faculty of Health and Society, Malmö University, Malmö SE-205 06, Sweden.
Olle SödermanDivision of Physical Chemistry, Lund University, P.O. Box 124, Lund SE-22100, Sweden.ORCID https://orcid.org/0000-0002-6360-0789
Vitaly KocherbitovDepartment of Biomedical Science, Faculty of Health and Society, Malmö University, Malmö SE-205 06, Sweden.ORCID https://orcid.org/0000-0002-9852-5440

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding water interactions in complex systems is crucial, as they play a key role in fields such as biochemistry, pharmaceutical formulations, and food science. Nuclear magnetic resonance (NMR) relaxation measurements have become one of the widely used methods to visualize various water characteristics owing to their noninvasive nature and ease of use. However, unambiguous data interpretation can be challenging and potentially misleading if not carefully analyzed. One such example is the observation of multiple relaxation times, which is often linked to different water types such as "bound" and "free". In this paper, we present a new approach for the interpretation of proton NMR relaxation data using a second-order reaction kinetics-based model. The case of first-order asymptotic analysis considering fast proton exchange is shown to be of particular relevance. The presented theory is tested using a series of sucrose-water and sucrose-D

Indexed as

low-field NMRproton NMR relaxationsolute−solvent interactionssucrose−water systemwater dynamics

Identifiers

PMID41624726
PMCPMC12856673

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.