Evidence map›Paper›PMID 41624594›Full record

ArticleMaternal-fetal medicine (Wolters Kluwer Health, Inc.)2026

The Effect of a Supervised Exercise Program Throughout Pregnancy on Longitudinal Lipid Profile Changes: A Randomized Clinical Trial.

Aránzazu Martín-Arias, Irene Fernández-Buhigas, Cristina Aramburu-Anglada, Adriana Aquise Pino, Rebeca Busto Sáez, Valeria Rolle, Miguel Sánchez-Polan, Cristina Silva-Jose, Maria M Gil, Belén Santacruz

Registry-linked trialAbstract read
In one paragraph

Article in Maternal-fetal medicine (Wolters Kluwer Health, Inc.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04563065 (Active Pregnancy, Prevention Against the Effects of COVID-19), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04563065 naunknown statusnot on this map

Active Pregnancy, Prevention Against the Effects of COVID-19

TypeinterventionalSponsorUniversidad Politecnica de MadridRan2020 to 2023Enrolled280ConditionsPregnancy Complications, Pregnancy, High Risk, Pregnancy Induced Hypertension, Newborn MorbidityArmsExercise program, Healthy lifestyle advise
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aránzazu Martín-AriasDepartment of Obstetrics and Gynecology, Hospital Universitario de Torrejón, Torrejón de Ardoz, Madrid 28850, Spain.
Irene Fernández-BuhigasDepartment of Obstetrics and Gynecology, Hospital Universitario de Torrejón, Torrejón de Ardoz, Madrid 28850, Spain.
Cristina Aramburu-AngladaDepartment of Obstetrics and Gynecology, Hospital Universitario de Torrejón, Torrejón de Ardoz, Madrid 28850, Spain.
Adriana Aquise PinoDepartment of Obstetrics and Gynecology, Hospital Universitario de Torrejón, Torrejón de Ardoz, Madrid 28850, Spain.
Rebeca Busto SáezFaculty of Statistical Studies, Universidad Complutense de Madrid, Madrid 28040, Spain.
Valeria RolleSpanish network in maternal, neonatal, child and developmental health research (RICORS-SAMID, RD24/0013/0018) Instituto de Salud Carlos III, Madrid 28040, Spain.
Miguel Sánchez-PolanGICAF Research Group, Department of Education, Research and Evaluation Methods, Universidad Pontificia Comillas, Madrid 28049, Spain.
Cristina Silva-JoseAFIPE Research Group, Faculty of Physical Activity and Sport Sciences-INEF, Universidad Politécnica de Madrid, Madrid 28040, Spain.
Maria M GilDepartment of Obstetrics and Gynecology, Hospital Universitario de Torrejón, Torrejón de Ardoz, Madrid 28850, Spain.
Belén SantacruzDepartment of Obstetrics and Gynecology, Hospital Universitario de Torrejón, Torrejón de Ardoz, Madrid 28850, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate whether a supervised exercise program during pregnancy induces modifications in the maternal lipid profile. Methods: This unplanned secondary analysis of a multicenter randomized controlled trial (March 2021-June 2023) was conducted at Hospital Universitario de Torrejón, the only participating center with routine lipid profiling during all three trimesters and postpartum. Eligible women had a singleton pregnancy < 14 Results: A total of 202 pregnant women were enrolled, and 182 were included in the final analysis (90 in the control group and 92 in the intervention group). No significant between-group differences were observed in lipid profiles at the second trimester, third trimester, or postpartum. Longitudinal analysis showed higher HDL-C levels in the IG (+3.24 mg/dl; 95% confidence interval ( Conclusion: A supervised exercise program throughout pregnancy may increase HDL-C levels and potentially reduce LDL-C, thereby improving the maternal lipid profile. Further studies are needed to confirm and expand upon these findings. Registration: No. NCT04563065 (Randomized Controlled Clinical Trial).

Indexed as

ExerciseLipidsLipoproteinsPregnancy

Identifiers

PMID41624594
PMCPMC12858217

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.