ArticleFrontiers in neurology
Immune alterations in vestibular neuritis: a retrospective database pilot study on T and B lymphocyte profiles and cytokine levels.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Vestibular neuritis (VN) etiology remains elusive, with hypotheses suggesting viral infection, non-infectious inflammation, or immune responses. Evaluating T and B Lymphocyte Subsets and cytokines gives a comprehensive snapshot of the body's immune function and inflammatory state. But comprehensive studies focusing on the T and B lymphocyte subsets and cytokine levels in VN are limited. This study aims to assess the T and B lymphocyte subsets and cytokine expressions in the blood of VN patients. This study shed light on its pathogenesis and provided valuable hematological markers for clinical prognosis. Methods: A retrospective analysis was conducted on subjects diagnosed with VN. Patients included exhibited acute, first-episode, persistent vertigo with accompanying symptoms of nausea, vomiting, postural instability, specific nystagmus, and positive head impulse test results. Exclusion criteria included hearing impairments, prior vestibular disorders, recent steroid therapy, and autoimmune conditions. Patients underwent blood tests (T and B lymphocyte subsets, cytokines) and DHI evaluations within days of onset, with a secondary assessment at discharge. Healthy individuals served as controls. Results: The study included 25 individuals with VN (aged 34-73 years, 13males) and 25 healthy controls (aged 33-74 years, 7males). VN patients exhibited elevated levels of total B lymphocytes, helper/inducer (CD3 Conclusion: Immunological perturbations are implicated in pathogenesis of VN. Evaluation of these immune markers could offer insights into prognostic outcomes for VN patients, leading to development of therapeutic strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.