Evidence map›Paper›PMID 41624543›Full record

ArticleFrontiers in neurology

Decoding the bilateral vestibulopathy spectrum: etiology-based phenotypes, clinical profiles and pathways to implant candidacy.

Joan Lorente-Piera, Raquel Manrique-Huarte, Ángel Ramos de Miguel, Ángel Ramos-Macías, Susana Benítez Robaina, Sebastián Picciafuoco, Manuel Manrique, Nicolás Pérez-Fernández

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Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joan Lorente-PieraDepartment of Otorhinolaryngology, Clínica Universidad de Navarra, Pamplona, Spain.
Raquel Manrique-HuarteDepartment of Otorhinolaryngology, Clínica Universidad de Navarra, Pamplona, Spain.
Ángel Ramos de MiguelCochlear Technology Centre Belgium, Mechelen, Belgium.
Ángel Ramos-MacíasDepartment of Otorhinolaryngology, Complejo Hospitalario Universitario Insular MaternoInfantil, Las Palmas de Gran Canaria, Spain.
Susana Benítez RobainaDepartment of Otorhinolaryngology, Complejo Hospitalario Universitario Insular MaternoInfantil, Las Palmas de Gran Canaria, Spain.
Sebastián PicciafuocoDepartment of Otorhinolaryngology, Clínica Universidad de Navarra, Pamplona, Spain.
Manuel ManriqueDepartment of Otorhinolaryngology, Clínica Universidad de Navarra, Pamplona, Spain.
Nicolás Pérez-FernándezDepartment of Otorhinolaryngology, Clínica Universidad de Navarra, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Bilateral vestibulopathy (BVP) is a chronic, disabling disorder characterized by bilateral loss of vestibular function, leading to imbalance, oscillopsia, and falls. Despite established diagnostic criteria, clinical expression and rehabilitation potential vary widely across etiologies. Understanding these functional signatures is crucial for tailoring future neurostimulation strategies. The main objective of this study is to decode the etiological and functional heterogeneity of BVP and define clinical-functional profiles guiding vestibular or cochleo-vestibular implant candidacy. Methods: A multicenter retrospective study included 119 adults fulfilling Bárány Society criteria for definite BVP (>1 year). Comprehensive audiovestibular testing comprised pure-tone audiometry (PTA), video head impulse test (vHIT), vestibular evoked myogenic potentials (VEMPs), and dynamic posturography (SOT, LOS). Group comparisons used Kruskal-Wallis and Dunn-Bonferroni tests; oscillopsia predictors were analyzed by binary logistic regression. Results: Etiologies included idiopathic (29.41%), Ménière's disease (26.89%), iatrogenic (18.49%), post-infectious (14.29%), cerebellar ataxia/CANVAS (6.72%), and post-traumatic (4.20%). Oscillopsia was reported by 48.74% and falls by 22.69%. Significant inter-etiological differences were found for semicircular canal gains ( Conclusion: BVP comprises etiology-specific phenotypes. Oscillopsia is driven mainly by VOR performance and PR index in LSC. Integrating auditory status, canal-otolith function, and compensation quality supports precision selection for vestibular versus cochleo-vestibular implantation.

Indexed as

bilateral vestibulopathyMénière diseasevestibular implantsvestibular rehabilitationvestibulotoxicity

Identifiers

PMID41624543
PMCPMC12855053

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