ArticleAmerican journal of preventive cardiology2026
Lifes essential 8 score and 10-year cardiovascular outcomes in atrial fibrillation: A UK biobank analysis with simulated lifestyle improvement.
Article in American journal of preventive cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Cardiovascular Health Among Employees of a Brazilian Tertiary Hospital Assessed by the Life's Essential 8 Score: A Cross-Sectional Pilot Study.Journal of clinical medicine · 2026Article
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Authors and funding
4 authors.
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Abstract
Background: Atrial fibrillation (AF) is associated with high risks of mortality and cardiovascular events, yet the prognostic value of comprehensive lifestyle and clinical health metrics remains uncertain. Objective: To investigate whether cardiovascular health (CVH), as measured by the American Heart Association's Life's Essential 8 (LE8) score, is associated with clinical outcomes in people with AF, and to estimate the impact of simulated improvement in CVH components. Methods: Data were drawn from the UK Biobank, a prospective population-based cohort. Participants with AF were identified using ICD codes. CVH was assessed using a modified LE8 score (range 0-100), derived from smoking status, cholesterol, blood pressure, BMI, HbA1c, physical activity, diet, and sleep. Primary outcomes were all-cause mortality and major adverse cardiovascular events (MACE: ischaemic heart disease, myocardial infarction, stroke, and heart failure). Associations were analysed using Cox models with penalised splines, presented in Kaplan-Meier curves. Population attributable and potential impact fractions were estimated. Results: Among 23,758 individuals with AF and 10-year follow-up, higher CVH scores associated with lower risk of all-cause mortality and MACE in a non-linear, graded pattern. Compared with the lowest quartile, the highest CVH quartile had 39% lower risk of all-cause mortality (HR: 0.61, 95% CI: 0.56-0.67) and 38% lower risk of MACE (HR: 0.62, 95% CI: 0.58-0.67; both Conclusion: Higher LE8 scores were independently associated with lower all-cause mortality and MACE risk in people with AF, supporting the role of lifestyle-based secondary prevention in AF care.
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