Evidence map›Paper›PMID 41624477›Full record

ArticleJournal of clinical imaging science2026

Primary cerebellar angiosarcoma: A rare case of posterior fossa vascular tumor with hemorrhagic presentation and favorable surgical outcome.

Yi Cong Chew, Po Yin Tang, Siang Hui Lai, Chi Long Ho

Abstract readCase Reports
In one paragraph

Article in Journal of clinical imaging science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Yi Cong ChewDepartment of Radiology, Sengkang General Hospital, Singapore.
Po Yin TangDepartment of Anatomical Pathology, Singapore General Hospital, Singapore.
Siang Hui LaiDepartment of Anatomical Pathology, Singapore General Hospital, Singapore.
Chi Long HoDepartment of Radiology, Sengkang General Hospital, Singapore.ORCID https://orcid.org/0000-0003-2216-1705

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary cerebellar angiosarcoma is an exceptionally rare intracranial malignancy, with only 22 cases reported in the literature. We report the case of a 67-year-old male who presented with a severe headache, unsteady gait, and giddiness. Computed tomography of the brain demonstrated a hemorrhagic lesion in the right cerebellar hemisphere with associated vasogenic edema and early hydrocephalus. Magnetic resonance imaging revealed a right cerebellar intra-axial lesion with mixed signal intensities and a characteristic peripheral "bull's eye" enhancement pattern. Histopathological evaluation showed a vasoformative neoplasm with atypical endothelial cells, high mitotic activity, and immunopositivity for CD31 and erythroblast transformation specific (ETS)-related gene (ERG), consistent with low-grade angiosarcoma. The patient underwent gross total resection and remained recurrence-free 16 months postoperatively. This case underscores the importance of multi-modality imaging in the early recognition of hemorrhagic cerebellar tumors and reinforces the role of radiological-pathological correlation in diagnosis and treatment planning. Given its rarity, diagnosis of cerebellar angiosarcoma requires a high index of suspicion, supported by advanced imaging and immunohistochemical profiling. Multidisciplinary management is essential, and further case documentation is necessary to guide therapeutic strategies and prognostication.

Indexed as

Case reportHemorrhagic cerebellar massPosterior fossa tumorPrimary central nervous system angiosarcomaSurgical resection

Identifiers

PMID41624477
PMCPMC12860322

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