Evidence map›Paper›PMID 41624339›Full record

ArticleSmall science2026

Preparation and Characterization of Niosomes for Bacteriophage Delivery.

Ashley Hannah George, Petr Jelinek, Martin Benešík, Simona Košiarčiková, Jiří Mikšátko, Ivona Pečurlić, Marek Moša, Miroslav Šoóš

Abstract read
In one paragraph

Article in Small science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ashley Hannah GeorgeDepartment of Chemical Engineering University of Chemistry and Technology Prague Technická 5 166 28 Prague 6 Czech Republic.
Petr JelinekDepartment of Chemical Engineering University of Chemistry and Technology Prague Technická 5 166 28 Prague 6 Czech Republic.
Martin BenešíkMB Pharma s.r.o. 120 00 Prague Czech Republic.
Simona KošiarčikováMB Pharma s.r.o. 120 00 Prague Czech Republic.
Jiří MikšátkoImaging Methods Core Facility BIOCEV Faculty of Science Charles University 252 50 Vestec Czech Republic.
Ivona PečurlićDepartment of Chemical Engineering University of Chemistry and Technology Prague Technická 5 166 28 Prague 6 Czech Republic.
Marek MošaMB Pharma s.r.o. 120 00 Prague Czech Republic.
Miroslav ŠoóšDepartment of Chemical Engineering University of Chemistry and Technology Prague Technická 5 166 28 Prague 6 Czech Republic.ORCID https://orcid.org/0000-0002-9742-7160

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vesicular nanocarriers, such as niosomes, are versatile systems for delivering therapeutic agents, including small molecules, proteins, enzymes, nucleic acids, and other biologics. Herein, the encapsulation of bacteriophages within niosomes is investigated, expanding the conventional application of these carriers. Formulations are prepared with varying concentrations of stearylamine, a cationic cosurfactant, to assess the interactions between phages and vesicular membranes. They are characterized by dynamic light scattering, zeta potential analysis, and viral titration, providing insights into vesicle stability and phage encapsulation efficiency. Based on the characterization analysis, an optimal concentration of stearylamine is determined for successful phage encapsulation, as confirmed by cryo-electron microscopy. The stability and activity of encapsulated phages are further evaluated through pH stability tests and in vitro kinetic assays. These findings demonstrate the potential of niosomes as effective carriers for bacteriophage delivery and highlight their broader applicability for encapsulating other unconventional or sensitive therapeutic agents, offering a promising strategy for antibacterial applications.

Indexed as

antibacterial therapybacteriabacteriophagesnanovesiclesniosomesstearylamine

Identifiers

PMID41624339
PMCPMC12854246

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.