Evidence map›Paper›PMID 41624295›Full record

ArticleHealthcare analytics (New York, N.Y.)2025

A Multi-Agent Reinforcement Learning Framework for Public Health Decision Analysis.

Dinesh Sharma, Ankit Shah, Chaitra Gopalappa

Abstract read
In one paragraph

Article in Healthcare analytics (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dinesh SharmaUniversity of South Florida, Department of Industrial and Management Systems Engineering, 4202 E Fowler Ave, Tampa, 33620, FL, USA.
Ankit ShahIndiana University, Department of Operations and Decision Technologies, 1309 E. 10th Street, Bloomington, 47405, IN, USA.
Chaitra GopalappaUniversity of Massachusetts Amherst, Department of Mechanical and Industrial Engineering, 300 Massachusetts Ave, Amherst, 01003, MA, USA.

Funding

Evaluating Portfolio Interventions for HIV Incidence Reduction in the United States: Development of a Novel Agent-Based Decision-Analytic Model for Dynamic Evaluations of InterventionsR01AI127236 · NIAID · UNIVERSITY OF MASSACHUSETTS AMHERST · PI GOPALAPPA, CHAITRA · 2017 to 2021
$1.6M
NIAID NIH HHS R01 AI127236
6 · The paper itself

Abstract

Human immunodeficiency virus (HIV) is a major public health concern in the United States (U.S.), with about 1.2 million people living with it and about 35,000 newly infected each year. There are considerable geographical disparities in HIV burden and care access across the U.S. The 'Ending the HIV Epidemic (EHE)' initiative by the U.S. Department of Health and Human Services aims to reduce new infections by 90% by 2030, by improving coverage of diagnoses, treatment, and prevention interventions and prioritizing jurisdictions with high HIV prevalence. One of the approaches towards achieving this objective includes developing intelligent decision-support systems that can help optimize resource allocation and intervention strategies. Existing decision analytic models either focus on individual cities or aggregate national data, failing to capture jurisdictional interactions critical for optimizing intervention strategies. To address this, we propose a multi-agent reinforcement learning (MARL) framework that enables jurisdiction-specific decision-making while accounting for cross-jurisdictional epidemiological interactions. Our framework functions as an intelligent resource optimization system, helping policymakers strategically allocate interventions based on dynamic, data-driven insights. Experimental results across jurisdictions in California and Florida demonstrate that MARL-driven policies outperform traditional single-agent reinforcement learning approaches by reducing new infections under fixed budget constraints. Our study highlights the importance of incorporating jurisdictional dependencies in decision-making frameworks for large-scale public initiatives. By integrating multi-agent intelligent systems, decision analytics, and reinforcement learning, this study advances expert systems for government resource planning and public health management, offering a scalable framework for broader applications in healthcare policy and epidemic management.

Indexed as

Decision Support SystemsEpidemic Resource AllocationHealth Intervention ModelingIntelligent Policy DesignPublic Health AnalyticsReinforcement Learning

Identifiers

PMID41624295
PMCPMC12858148

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.