Evidence map›Paper›PMID 41624210›Full record

ArticleJHLT open2026

Bronchial stenosis after lung transplant: Risk factors and clinical outcomes.

Antonio Coppolino, Rie Maurer, Ella Woehl, Erin M Connolly, Elene Chamberlin, Hilary J Goldberg, Selvin S Jacob, Stefi F Lee, John C Kennedy, Adil Sheikh and 10 more

Abstract read
In one paragraph

Article in JHLT open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Antonio CoppolinoBrigham and Women's Hospital, Boston, MA.
Rie MaurerHarvard Catalyst, Boston, MA.
Ella WoehlBrigham and Women's Hospital, Boston, MA.
Erin M ConnollyBrigham and Women's Hospital, Boston, MA.
Elene ChamberlinBrigham and Women's Hospital, Boston, MA.
Hilary J GoldbergBrigham and Women's Hospital, Boston, MA.
Selvin S JacobBrigham and Women's Hospital, Boston, MA.
Stefi F LeeBrigham and Women's Hospital, Boston, MA.
John C KennedyBrigham and Women's Hospital, Boston, MA.
Adil SheikhBrigham and Women's Hospital, Boston, MA.
Audra J O'NeillBrigham and Women's Hospital, Boston, MA.
Simran GuptaBrigham and Women's Hospital, Boston, MA.
Ruben A Hernandez AcostaBrigham and Women's Hospital, Boston, MA.
Victor KovacBrigham and Women's Hospital, Boston, MA.
Mohamed KeshkBrigham and Women's Hospital, Boston, MA.
Amy HackmannBrigham and Women's Hospital, Boston, MA.
John DunningBrigham and Women's Hospital, Boston, MA.
Nirmal S SharmaBrigham and Women's Hospital, Boston, MA.
Lindsey R BadenBrigham and Women's Hospital, Boston, MA.
Ann E WoolleyBrigham and Women's Hospital, Boston, MA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bronchial stenosis is a known complication after lung transplantation, but risk factors remain incompletely understood. We identified predictors of bronchial stenosis requiring bronchoscopic intervention, with a focus on post-transplant bacterial infections, and its impact on clinical outcomes. Methods: We conducted a retrospective cohort study of 342 adult lung transplant recipients at a single center between 2017 and 2023. Bronchial stenosis was defined as localized airway narrowing requiring intervention. Clinical, perioperative, and infectious variables-censored to precede the onset of stenosis-were analyzed using univariate and multivariable logistic regression. Outcomes included survival, acute cellular and antibody-mediated rejection, and chronic lung allograft dysfunction (CLAD). Results: Thirty-four patients (9.9%) developed bronchial stenosis requiring intervention. Multivariable analysis identified male sex (OR: 2.77, 95% CI: 1.13-6.79, Conclusions: Bronchial stenosis following lung transplantation is associated with PGD and bacterial airway infections, particularly

Indexed as

Bronchial stenosisGram-negative bacterial airway infectionsLung transplantationPulmonary graft dysfunction

Identifiers

PMID41624210
PMCPMC12857399

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.