Evidence map›Paper›PMID 41623968›Full record

ReviewFood chemistry: X2026

From waste to wellness: Citrus by-products as nutritional and immunological enhancers in aquaculture.

Yu Wang, Meng-Ze Nie, Ping Shi, Yuan-Sen Liu, Wei-Bing Lan, Zi-Ru Dai, Muhammad Adeel, Hafiz Umer Javed

Abstract readReview
In one paragraph

Review in Food chemistry: X, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yu WangGuangxi Zhuang Autonomous Region Engineering Research Center of Marine Food Nutrition and Processing Technology Innovation, Guangxi College and University Key Laboratory of High-value Utilization of Seafood and Prepared Food in Beibu Gulf, Beibu Gulf University, Qinzhou 535011, China.
Meng-Ze NieGuangxi Zhuang Autonomous Region Engineering Research Center of Marine Food Nutrition and Processing Technology Innovation, Guangxi College and University Key Laboratory of High-value Utilization of Seafood and Prepared Food in Beibu Gulf, Beibu Gulf University, Qinzhou 535011, China.
Ping ShiGuangxi Zhuang Autonomous Region Engineering Research Center of Marine Food Nutrition and Processing Technology Innovation, Guangxi College and University Key Laboratory of High-value Utilization of Seafood and Prepared Food in Beibu Gulf, Beibu Gulf University, Qinzhou 535011, China.
Yuan-Sen LiuGuangxi Zhuang Autonomous Region Engineering Research Center of Marine Food Nutrition and Processing Technology Innovation, Guangxi College and University Key Laboratory of High-value Utilization of Seafood and Prepared Food in Beibu Gulf, Beibu Gulf University, Qinzhou 535011, China.
Wei-Bing LanGuangxi Zhuang Autonomous Region Engineering Research Center of Marine Food Nutrition and Processing Technology Innovation, Guangxi College and University Key Laboratory of High-value Utilization of Seafood and Prepared Food in Beibu Gulf, Beibu Gulf University, Qinzhou 535011, China.
Zi-Ru DaiGuangxi Zhuang Autonomous Region Engineering Research Center of Marine Food Nutrition and Processing Technology Innovation, Guangxi College and University Key Laboratory of High-value Utilization of Seafood and Prepared Food in Beibu Gulf, Beibu Gulf University, Qinzhou 535011, China.
Muhammad AdeelBeijing Normal University at Zhuhai, Zhuhai, Guangdong 519087, China.
Hafiz Umer JavedGuangxi Zhuang Autonomous Region Engineering Research Center of Marine Food Nutrition and Processing Technology Innovation, Guangxi College and University Key Laboratory of High-value Utilization of Seafood and Prepared Food in Beibu Gulf, Beibu Gulf University, Qinzhou 535011, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aquaculture industry plays a vital role in global protein supply; however, it faces significant challenges, including escalating feed costs, disease outbreaks, and concerns over environmental sustainability. Citrus by-products offer a valuable and underutilized renewable resource for developing functional aquafeeds. Green extraction technologies, particularly ultrasound-assisted extraction, have demonstrated high efficiency in recovering bioactive compounds, increasing phenolic yields by more than 30 % while substantially reducing solvent consumption. The inclusion of citrus-derived bioactive in aquafeeds enhances growth performance, immune function, and disease resistance in aquatic species. For example, dietary supplementation with lemon peel extracts improved survival in Nile tilapia to over 80 %, while bitter orange essential oil increased growth rate and modulated immune-related gene expression in common carp. Despite these promising results, bioavailability, metabolic pathways, and species-specific responses remain insufficiently understood. This review synthesizes advances in green extraction and functional applications of citrus bioactives, identifying critical research gaps to guide sustainable aquaculture innovation.

Indexed as

Bioactive compoundsCitrus by-productsExtraction techniquesFish health

Identifiers

PMID41623968
PMCPMC12853054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.