Evidence map›Paper›PMID 41623942›Full record

ReviewBiomaterials translational2025

An exploration into the principles and theoretical progress of fracture treatment based on the mechanism of fracture healing.

Haiming Ye, Qi Yang, Jiadi Hou, Xuan Zhang, Yien Zheng, Tiantian Qi, Fei Yu

Abstract readReview
In one paragraph

Review in Biomaterials translational, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haiming YeDepartment of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen, Guangdong Province, China.
Qi YangDepartment of Ultrasound Medicine, Peking University Shenzhen Hospital, Shenzhen, Guangdong Province, China.
Jiadi HouEndoscopy Room, Binchen District Municipal Hospital, Binzhou, Shandong Province, China.
Xuan ZhangDepartment of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen, Guangdong Province, China.
Yien ZhengInstitute of Macromolecular Chemistry, University of Freiburg, Freiburg, Germany.
Tiantian QiDepartment of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen, Guangdong Province, China.
Fei YuDepartment of Spine Surgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fractures are a common category of diseases in the field of orthopaedics with a high incidence in archaeologically obtained bones. These diseases may occur in various human activities. In the context of technological advancement, the annual incidence of fractures is increasing due to traffic accidents, sports injuries, and ageing. Besides, the classification of fracture diseases is also changing, making them one of the main orthopaedic diseases that affect the quality of life of patients and national medical expenditure. There are some basic principles in the treatment of fractures, and the understanding of the causes, types, and pathogenesis of fractures is constantly improved with technological development. Hence, there are sustained efforts to explore fracture treatment methods and examine even widely popular concepts, such as Arbeitsgemeinschaft für Osteosynthesis (AO) and biological osteosynthesis (BO) principles. However, nonhealing fractures, fracture infections, and other treatment problems can still not be eliminated based on these concepts. In addition, some new perspectives on the treatment principles of fractures have been proposed by surgeons based on their clinical experience. In this paper, the latest research results on fracture healing are summarised, and our views and opinions on the application of AO or other new concepts in fracture treatment are also elucidated. During the investigation of the advantages and disadvantages of fracture treatment concepts, the shortcomings of current fracture treatment strategies or theories are also reviewed. These findings may provide clinicians with theoretical support for fracture treatment and inspire scholars to delve into fracture treatment principles.

Indexed as

AO principlesFractureHealing mechanismTherapeutic theoryTreatment principles

Identifiers

PMID41623942
PMCPMC12852076

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.