ArticleJournal of the Endocrine Society2026
Bone Age Delay in X-linked Hypophosphatemia.
Article in Journal of the Endocrine Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
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Abstract
Context: Bone age (BA) assessment and prediction of adult height (AdHt) has not been well studied in children with X-linked hypophosphatemia (XLH). Objective: To assess BA and its utility in height prediction in children with XLH. Design: Retrospective, cross-sectional, and longitudinal assessments of BA using 2 standard methods in children with XLH. Mean values were used to calculate predicted adult height (PAH), which was compared to final or near-final AdHt in patients who were at or near the end of growth. Setting: Academic medical center. Patients: Fifty-six children with XLH. Intervention: None. Main Outcome Measures: BA, PAH. Results: Initial radiographs demonstrated BA delay (chronologic age-BA) of 1.2 ± 1.0 (mean ± SD) years in males and 0.4 ± 1.0 years in females (greater delay in males, Conclusion: BA is delayed in children with XLH but more strikingly so in males. Height predictions were within a range typically used in healthy children (±2 inches). The Bayley-Pinneau method appears to modestly overestimate AdHt in males, whereas Tanner-Whitehouse overestimates AdHt in females.
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