ArticleDEN open2026
Clinical Outcomes and Learning Curve of Endoscopic Ultrasound-Guided Hepaticogastrostomy During the Implementation Phase in Inexperienced Centers: A Multicenter Retrospective Study.
Article in DEN open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
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Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Endoscopic ultrasound-guided hepaticogastrostomy (EUS-HGS) is a technically demanding procedure performed predominantly at centers with high expertise. Its feasibility and learning curves in inexperienced centers remain unclear. This study aimed to evaluate the initial clinical outcomes and learning curves of EUS-HGS implemented in inexperienced centers. Methods: Between September 2018 and December 2020, four tertiary care centers specializing in pancreaticobiliary disease implemented EUS-HGS. The first 20 patients who underwent EUS-HGS at each institution were retrospectively enrolled. The primary outcomes were technical success, procedure time, and serious (moderate-to-severe) adverse events (AEs). A learning curve analysis was conducted using chronological quartiles. Logistic regression was used to identify the predictors of technical failure and serious AEs. Results: The overall technical success rate was 94% (75/80); serious AEs occurred in 11% (9/80). Procedure time significantly decreased across quartiles, whereas no significant trend was observed for technical success or serious AE rates. The univariate analysis did not identify significant predictors of technical failure, whereas the multivariate analysis identified ascites as an independent predictor of serious AEs. Conclusions: EUS-HGS can be feasibly implemented with caution in inexperienced centers, particularly when performed by endoscopists with adequate pancreatobiliary expertise. Additionally, during the implementation phase, procedure time decreased with increasing institutional experience.
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Registered trials
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