Evidence map›Paper›PMID 41623867›Full record

ArticleFrontiers in cardiovascular medicine2025

When similar is not the same: sex-specific outcomes and risk factors in thoracoabdominal aortic repair.

Florian Helms, Heike Krüger, Ezin Deniz, Alina Botezatu, Andreas Martens, Aron-Frederik Popov, Stefan Rümke, Bastian Schmack, Jan Dieter Schmitto, Alexander Weymann and 2 more

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Florian HelmsDivision for Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Heike KrügerDivision for Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Ezin DenizDivision for Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Alina BotezatuDivision for Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Andreas MartensClinic for Cardiac Surgery, University Clinic Oldenburg, Oldenburg, Germany.
Aron-Frederik PopovClinic for Cardiac Surgery, Asklepios Clinic Harburg, Hamburg, Germany.
Stefan RümkeDivision for Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Bastian SchmackDivision for Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Jan Dieter SchmittoDivision for Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Alexander WeymannDivision for Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Arjang RuhparwarDivision for Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Morsi ArarDivision for Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Growing evidence suggests major outcome and risk factor disparities between men and women undergoing cardiovascular surgery. Thus, sex-specific approaches are increasingly being adopted in cardiovascular medicine. However, data on sex-specific outcomes and risk stratification in complex thoracoabdominal aortic repair remain limited. Methods: We present a retrospective single-center analysis of 311 consecutive patients, including 99 women (31.8%), who underwent open surgical thoracoabdominal aortic repair between 2000 and 2024. Propensity score matching was performed prior to a comparative analysis of intraoperative parameters, postoperative outcome, and complications, as well as short- and long-term mortality between female and male patients. Results: In the initial study population, men had a significantly higher BMI (26.3 vs. 23.1 kg/m Conclusion: Overall outcomes and survival following thoracoabdominal aortic repair were comparable between men and women. However, underlying risk factors for early mortality differed fundamentally between sexes. These findings underscore the importance of a sex-specific preoperative risk assessment in the surgical decision-making process prior to open thoracoabdominal aortic repair.

Indexed as

aortic aneurysmaortic surgeryindividualized therapysex-specific analysisthoracoabdominal aorta

Identifiers

PMID41623867
PMCPMC12856921

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.