Comparative study on salivary IL- 8 and LDH among tobacco users without lesions, leukoplakia, oral submucous fibrosis and oral squamous cell carcinoma.

Srinivasan Venkatesh, Saraswathi Gopal K, Nandhini Ganesan

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Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 authors.

Srinivasan VenkateshDepartment of Oral medicine and Radiology, Meenakshi Ammal Dental College and Hospital, MAHER University, Chennai, India.

Saraswathi Gopal KDepartment of Oral medicine and Radiology, Meenakshi Ammal Dental College and Hospital, MAHER University, Chennai, India.

Nandhini GanesanDepartment of Oral medicine and Radiology, Meenakshi Ammal Dental College and Hospital, MAHER University, Chennai, India.

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6 · The paper itself

Abstract

Oral and oropharyngeal malignancies, OSCC accounts for 95% of cases. Diagnosis and prognosis of OSCC relies upon the tumour staging, an important predictor of survival. Therefore, it is of interest to evaluate the changes in the salivary levels of IL-8 and LDH among Tobacco users without lesions, Individuals with Leukoplakia, Oral submucous fibrosis and OSCC. 40 cases were analysed in this study. We show that salivary IL8 and LDH which can serve as one reliable biomarker in early detection of OSCC and a prognostic indicator for OPMDs.

Indexed as

ELISAInterleukin-8Lactate dehydrogenase (LDH)oral squamous cell carcinomasaliva

Identifiers

PMID41623779

DOI10.6026/973206300213542

PMCPMC12859366

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