Evidence map›Paper›PMID 41623768›Full record

ArticleBioinformation2025

Assessing anti-plaque efficiency of a herbal dentifrice.

Debadrita Ghosh, Vishal Yadav, Sonia Sharma, Nagaraja A, Nandini Komaravelli, Shali Singh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Debadrita GhoshDepartment of Pediatric & Preventive Dentistry, Consultant Pedodontist, Kolkata, West Bengal, India.
Vishal YadavDepartment of Dentistry, Government Medical College, Bundi, Rajasthan, India.
Sonia SharmaDepartment of Dentistry, Maharaja Agrasen Medical College, Agroha, Haryana, India.
Nagaraja ADepartment of Oral & Maxillofacial Pathology, Seema Dental College & Hospital, Rishikesh, Uttarakhand, India.
Nandini KomaravelliDepartment of Periodontology and Implantology, SVS Institute of Dental Sciences, Mahbubnagar, Telangana, India.
Shali SinghDepartment of Pedodontics & Preventive Dentistry, Safdarjung Hospital, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dental plaque is a key factor in gingivitis and periodontitis, requiring effective control measures. This randomized, double-blind clinical trial compared an herbal dentifrice (neem, clove and tea tree oil), a conventional fluoride dentifrice and a placebo in 90 participants with mild gingivitis. Plaque Index (PI) and Gingival Index (GI) were recorded at baseline, 2 weeks and 4 weeks. At 4 weeks, the herbal dentifrice showed the greatest reductions in PI (60.7%) and GI (55.7%) compared to fluoride (48.6%, 41.8%) and placebo (21.4%, 13.2%), with significant intergroup differences (p < 0.001). The herbal dentifrice demonstrated superior anti-plaque and anti-gingivitis efficacy, supporting its role as a natural oral hygiene alternative.

Indexed as

Azadirachta indicaclinical trialdental plaquegingivitisHerbal dentifriceMelaleuca alternifoliaoral hygieneSyzygium aromaticum

Identifiers

PMID41623768
PMCPMC12859292

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.