ArticleBioinformation2025
Assessing healing of periapical pathologies by platelet-rich fibrin: A clinical study.
Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Improbable healing in endodontics: a case series of favorable outcomes despite adverse prognostic conditions.BMC oral health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the on-going clinical challenges in endodontic microsurgery is the regeneration of massive periapical lesions. Hence, a Forty patients participated in this randomized controlled clinical experiment to see how well platelet-rich fibrin (PRF) worked as a scaffold for regeneration in comparison to the body's inherent ability to mend blood clots. The decrease in lesion volume, pain ratings, and the repair of soft tissues were evaluated at 6 and 12 months by CBCT. PRF demonstrated a much higher rate of bone regeneration (85.2% vs. 64.8%, p < 0.001) and reduced levels of post-operative discomfort on days 1 and 3. Thus, we show that PRF is an inexpensive and easy way to improve the predictability of recovery after periapical surgery.
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Registered trials
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