Evidence map›Paper›PMID 41623496›Full record

ArticleiScience2026

LAR1 promotes breast carcinogenesis by activating NF-κB signaling pathway through binding and enhancing APOC1 expression.

Jiayi Xiao, Qi Li, Zhu Li, Lingxin Kong, Yang Shang, Yongliang Xu, Mo Dong, Sijin Zhang, Zitao Li, Caijuan Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jiayi XiaoDepartment of Ultrasound, Hongqi Hospital Affiliated to Mudanjiang Medical University, Mudanjiang, Heilongjiang, China.
Qi LiDepartment of Nuclear Magnetic Resonance, Hongqi Hospital Affiliated to Mudanjiang Medical University, Mudanjiang, Heilongjiang, China.
Zhu LiDepartment of Teaching and Research Section, School of Medical Imaging, Mudanjiang Medical University, Mudanjiang, Heilongjiang, China.
Lingxin KongDepartment of Ultrasound, Hongqi Hospital Affiliated to Mudanjiang Medical University, Mudanjiang, Heilongjiang, China.
Yang ShangDepartment of Ultrasound, Hongqi Hospital Affiliated to Mudanjiang Medical University, Mudanjiang, Heilongjiang, China.
Yongliang XuDepartment of Anatomy, School of Basic Medical Science, Mudanjiang Medical University, Mudanjiang, Heilongjiang, China.
Mo DongDepartment of Teaching and Research Section, School of Medical Imaging, Mudanjiang Medical University, Mudanjiang, Heilongjiang, China.
Sijin ZhangDepartment of Equipment Teaching and Research Section, School of Medical Imaging, Mudanjiang Medical University, Mudanjiang, Heilongjiang, China.
Zitao LiDepartment of Orthopedic Surgery, Hongqi Hospital Affiliated to Mudanjiang Medical University, Mudanjiang, Heilongjiang, China.
Caijuan LiDepartment of Ultrasound, Hongqi Hospital Affiliated to Mudanjiang Medical University, Mudanjiang, Heilongjiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer (BC) remains a leading cause of cancer-related mortality in women worldwide. Through online data mining, we identified the significant upregulation of the RNA-binding protein La Ribonucleoprotein 1 (LAR1) in BC. Functionally, LAR1 knockdown impeded S-phase entry, migration, and invasion of BC cells

Indexed as

CancerMolecular biology

Identifiers

PMID41623496
PMCPMC12859215

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.