Evidence map›Paper›PMID 41623485›Full record

ArticleiScience2026

Optimized primer and model improve precision of X chromosome telomere length determination in the Han population.

Zhiqi Zhang, Xiangdong Sun, Jianxiang Shi, Hongen Xu, Haoyu Wang, Zhaohui Yang, Jiancheng Guo, Zengguang Yang, Chenxi Li, Jicun Zhu and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Zhiqi ZhangHenan Key Laboratory for Helicobacter pylori and Digestive Tract Microbiology, The Fifth Affiliated Hospital of Zhengzhou University, Institute of Rehabilitation Medicine, Henan Academy of Innovations in Medical Science, Tianjian Laboratory of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou 450000, Henan, China.
Xiangdong SunHenan Key Laboratory for Helicobacter pylori and Digestive Tract Microbiology, The Fifth Affiliated Hospital of Zhengzhou University, Institute of Rehabilitation Medicine, Henan Academy of Innovations in Medical Science, Tianjian Laboratory of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou 450000, Henan, China.
Jianxiang ShiHenan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450052, Henan, China.
Hongen XuState Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Academy of Medical Sciences, Tianjian Laboratory of Advanced Biomedical Sciences, Zhengzhou University, N 40 Daxue Road, Zhengzhou 450052, China.
Haoyu WangHenan Key Laboratory for Helicobacter pylori and Digestive Tract Microbiology, The Fifth Affiliated Hospital of Zhengzhou University, Institute of Rehabilitation Medicine, Henan Academy of Innovations in Medical Science, Tianjian Laboratory of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou 450000, Henan, China.
Zhaohui YangState Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Academy of Medical Sciences, Tianjian Laboratory of Advanced Biomedical Sciences, Zhengzhou University, N 40 Daxue Road, Zhengzhou 450052, China.
Jiancheng GuoState Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Academy of Medical Sciences, Tianjian Laboratory of Advanced Biomedical Sciences, Zhengzhou University, N 40 Daxue Road, Zhengzhou 450052, China.
Zengguang YangState Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Academy of Medical Sciences, Tianjian Laboratory of Advanced Biomedical Sciences, Zhengzhou University, N 40 Daxue Road, Zhengzhou 450052, China.
Chenxi LiThe First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China.
Jicun ZhuThe First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China.
Yuexiao ZhangHenan Key Laboratory for Helicobacter pylori and Digestive Tract Microbiology, The Fifth Affiliated Hospital of Zhengzhou University, Institute of Rehabilitation Medicine, Henan Academy of Innovations in Medical Science, Tianjian Laboratory of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou 450000, Henan, China.
Pengyuan ZhengHenan Key Laboratory for Helicobacter pylori and Digestive Tract Microbiology, The Fifth Affiliated Hospital of Zhengzhou University, Institute of Rehabilitation Medicine, Henan Academy of Innovations in Medical Science, Tianjian Laboratory of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou 450000, Henan, China.
Xia XueHenan Key Laboratory for Helicobacter pylori and Digestive Tract Microbiology, The Fifth Affiliated Hospital of Zhengzhou University, Institute of Rehabilitation Medicine, Henan Academy of Innovations in Medical Science, Tianjian Laboratory of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou 450000, Henan, China.
Yang MiHenan Key Laboratory for Helicobacter pylori and Digestive Tract Microbiology, The Fifth Affiliated Hospital of Zhengzhou University, Institute of Rehabilitation Medicine, Henan Academy of Innovations in Medical Science, Tianjian Laboratory of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou 450000, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The attrition of telomere length is associated with cellular aging and plays a role in multiple age-related disorders. This study analyzed the relationship between telomere length on the X chromosome and age in the Han population (

Indexed as

bioinformaticsbiological sciencesgenomicsmethodology in biological sciencesneural networks

Identifiers

PMID41623485
PMCPMC12856150

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.