ArticleiScience2026
Retinal Cx36 gap junctions in the inner and outer plexiform layers differentially control visual thresholds.
Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Gap junctions are important components of signal communication in sensory systems. In the retina, connexin 36 (Cx36) gap junctions integrate visual signals over space and time. However, we do not understand how Cx36 gap junctions in the inner- and outer-retina govern visual thresholds under dim light conditions. Here we address this question using transgenic mouse models, an operant behavioral assay, and psychophysical modeling. Visual thresholds with Ganzfeld illumination decreased with flash durations <0.5 s, plateauing at ∼2 × 10
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