Evidence map›Paper›PMID 41623452›Full record

ArticleiScience2026

Structure and function of persulfide dioxygenase from

Francesca Giordano, Francesca Troilo, Martina Roberta Nastasi, Lorenzo Caruso, Marta Mellini, Carlo Travaglini-Allocatelli, Giorgio Giardina, João B Vicente, Giordano Rampioni, Adele Di Matteo and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Francesca GiordanoDepartment of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, 00185 Rome, Italy.
Francesca TroiloInstitute of Molecular Biology and Pathology, National Research Council, 00185 Rome, Italy.
Martina Roberta NastasiDepartment of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, 00185 Rome, Italy.
Lorenzo CarusoDepartment of Science, Roma Tre University, 00146 Rome, Italy.
Marta MelliniDepartment of Science, Roma Tre University, 00146 Rome, Italy.
Carlo Travaglini-AllocatelliDepartment of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, 00185 Rome, Italy.
Giorgio GiardinaDepartment of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, 00185 Rome, Italy.
João B VicenteInstituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal.
Giordano RampioniDepartment of Science, Roma Tre University, 00146 Rome, Italy.
Adele Di MatteoInstitute of Molecular Biology and Pathology, National Research Council, 00185 Rome, Italy.
Elena ForteDepartment of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, 00185 Rome, Italy.
Alessandro GiuffrèInstitute of Molecular Biology and Pathology, National Research Council, 00185 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogen sulfide is an important signaling molecule, beneficial at physiological concentrations but harmful at higher levels, due to which a tight control of its bioavailability is essential. Here, we investigated persulfide dioxygenase, an enzyme involved in H

Indexed as

biochemistrymicrobiologystructural biology

Identifiers

PMID41623452
PMCPMC12856154

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.