Evidence map›Paper›PMID 41623297›Full record

ArticleKidney medicine2026

Fluid Management Based on Bioimpedance, Blood Volume, and Patient Reports: A Quality Improvement Project in Maintenance Hemodialysis.

Sebastian Mussnig, Luis Naar, Simon Krenn, Florian Brosch, Daniel Schneditz, Joachim Beige, Manfred Hecking

Abstract read
In one paragraph

Article in Kidney medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Is Anything Gained From Estimating Blood Volume in Hemodialysis From Extracellular Volume Divided by a Constant Factor?Hemodialysis international. International Symposium on Home Hemodialysis · 2026
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sebastian MussnigDepartment of Epidemiology, Center for Public Health, Medical University of Vienna, Vienna, Austria.
Luis NaarDepartment of Epidemiology, Center for Public Health, Medical University of Vienna, Vienna, Austria.
Simon KrennDepartment of Epidemiology, Center for Public Health, Medical University of Vienna, Vienna, Austria.
Florian BroschDepartment of Medicine III, Division for Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria.
Daniel SchneditzDivision of Physiology & Pathophysiology, Otto Loewi Research Center for Vascular Biology, Immunology and Inflammation, Medical University of Graz, Graz, Austria.
Joachim BeigeKuratorium for Dialysis and Transplantation e.V. (KfH), Neu-Isenburg, Germany.
Manfred HeckingDepartment of Epidemiology, Center for Public Health, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rationale & Objective: Fluid management in hemodialysis aims to remove excess fluid while avoiding symptoms of fluid depletion. This study evaluated the impact of determining euvolemic body mass by bioimpedance spectroscopy, and absolute blood volume (ABV), on clinical practice and patient-reported outcome measures (PROMs) at a bioimpedance/ABV-naïve dialysis center. Study Design: Fourteen week quality improvement project with 3 Assessment phases separated by 2 Adjustment phases. Setting & Participants: Total of 127 patients at a single dialysis center. Quality Improvement Activities: Bioimpedance-spectroscopy-derived fluid overload (FO), ABV, and PROMs were longitudinally recorded. Physicians received data from each Assessment phase to inform treatment decisions. Outcomes: Fluid overload, ABV, PROMs, and agreement between perceived fluid status and FO. Analytic Approach: Generalized linear mixed-effects models analyzed changes over time and associations between FO, ABV, and PROMs. Agreement between perceived fluid status and FO was evaluated with linearly weighted Cohen's κ. Results: With each Assessment phase, pre-dialysis FO, systolic and diastolic blood pressure decreased overall (-0.12 L, Conclusions: During the introduction of bioimpedance- and ABV-guided fluid management at a hemodialysis center, fluid status improved without significant changes in intradialytic morbid events. The lack of agreement between perceived fluid status and bioimpedance-spectroscopy-derived FO reflects the daily clinical struggle when negotiating fluid management based on objective measures.

Indexed as

bioimpedanceblood volumefluid managementHemodialysispatient-reported outcome measuresultrafiltration

Identifiers

PMID41623297
PMCPMC12856452

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.