Evidence map›Paper›PMID 41623273›Full record

ArticleInternational journal of technology assessment in health care2026

Barriers to the application of Health Technology Assessment (HTA) results: the case of COVID-19 vaccine deployment in Ghana.

Brian Adu Asare, Emmanuella Abassah-Konadu, Sarah Ama Kafui Okine, Ivy Amankwah, Desmond Dzidzornu Otoo, Hannah Asante, Saviour Yevutsey, Maxwell Ayindenaba Dalaba, Mustapha Immurana, Matilda Aberese-Ako and 9 more

Abstract read
In one paragraph

Article in International journal of technology assessment in health care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Brian Adu AsareHealth Technology Assessment Secretariat, https://ror.org/05c7h4935Ministry of Health, Ghana.ORCID https://orcid.org/0000-0003-2216-501X
Emmanuella Abassah-KonaduHealth Technology Assessment Secretariat, https://ror.org/05c7h4935Ministry of Health, Ghana.
Sarah Ama Kafui Okinehttps://ror.org/05c7h4935Ministry of Health, Ghana.
Ivy AmankwahHealth Technology Assessment Secretariat, https://ror.org/05c7h4935Ministry of Health, Ghana.
Desmond Dzidzornu OtooHealth Technology Assessment Technical Working Group, https://ror.org/05c7h4935Ministry of Health, Ghana.
Hannah AsanteHealth Technology Assessment Secretariat, https://ror.org/05c7h4935Ministry of Health, Ghana.
Saviour YevutseyHealth Technology Assessment Secretariat, https://ror.org/05c7h4935Ministry of Health, Ghana.
Maxwell Ayindenaba Dalabahttps://ror.org/054tfvs49University of Health and Allied Sciences, Ghana.
Mustapha Immuranahttps://ror.org/054tfvs49University of Health and Allied Sciences, Ghana.
Matilda Aberese-Akohttps://ror.org/054tfvs49University of Health and Allied Sciences, Ghana.
Joycelyn AzeezHealth Technology Assessment Technical Working Group, https://ror.org/05c7h4935Ministry of Health, Ghana.
Edith Enyonam GavorPublic Health Specialist, Ghana.
Martha Gyansa-LutterodtGhana College of Pharmacists, Public Health, Ghana.
Evelyn Ansahhttps://ror.org/054tfvs49University of Health and Allied Sciences, Ghana.
Tuoyo OkorosoboSAVING Consortium.
Olumide OgundahunsiSAVING Consortium.
Abraham HodgsonSAVING Consortium.
Seth Owusu Agyeihttps://ror.org/054tfvs49University of Health and Allied Sciences, Ghana.
Margaret Gyaponghttps://ror.org/054tfvs49University of Health and Allied Sciences, Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesHealth Technology Assessment (HTA) guides healthcare decision-making, while Implementation Research (IR) addresses challenges in operationalizing these decisions. The SAVING (Sustainable Access and Delivery of New Vaccines in Ghana) Consortium aims to enhance health intervention delivery in Ghana, focusing on HTA evidence. This study identifies barriers to the application of HTA-related evidence (cost analysis) in coronavirus disease 2019 (COVID-19) vaccine deployment in Ghana.

methodsThis qualitative exploratory study purposively selected 12 key stakeholders with high interest and power relating to COVID-19 vaccine deployment in Ghana. Through in-depth interviews, seven stakeholders from diverse sectors contributed insights into barriers to the application of HTA-related evidence. Thematic analysis was conducted with narrative reporting supported by direct quotes for substantiation.

resultsSix main barriers were identified: (1) timing and access to HTA reports, (2) technical complexities, (3) relevance of content, (4) political considerations and power dynamics, (5) health system fragmentation, and (6) poor responsiveness of decision-makers to research. Proposed solutions include engaging political decision-makers continuously, simplifying technical reports, aligning report content with policymakers' needs, reducing political considerations, enhancing capacity building, fostering health system cohesion, and improving responsiveness to research.

conclusionsHTA is vital for informed healthcare decisions. However, technical complexity, relevance of content, inappropriate timing, and lack of access to HTA reports, among other barriers, prevent the uptake of HTA findings. Continuous and improved engagement between HTA producers and policymakers, along with rapid production of HTA, has the potential to improve the uptake of HTA findings, even during public health emergencies.

Indexed as

COVID-19COVID-19 VaccinesTechnology Assessment, BiomedicalDecision MakingGhanaHumansQualitative ResearchSARS-CoV-2COVID-19 VaccinesAccess and DeliverybarriersCOVID-19GhanaHealth Technology Assessmentpolicy recommendationspublic health emergenciesvaccine deployment

Identifiers

PMID41623273
PMCPMC12951341

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.