Evidence map›Paper›PMID 41623250›Full record

ArticleEpidemiology and infection2026

Epidemiology and risk analysis of Powassan virus infection, New York state, USA, 2013-2023.

Angelina R Varon, Melissa A Prusinski, Collin O'Connor, Joseph G Maffei, Lindsay Tomaszek, Jessica Stout, Anne F Payne, Alan P Dupuis, Alexander T Ciota, Kyle Carson and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epidemiology and infection, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Angelina R VaronAssociation of Public Health Laboratories, USA.ORCID https://orcid.org/0009-0002-3815-493X
Melissa A PrusinskiBureau of Communicable Disease Control, New York State Department of Health, USA.
Collin O'ConnorBureau of Communicable Disease Control, New York State Department of Health, USA.
Joseph G MaffeiThe Arbovirus Laboratory, New York State Department of Health, Wadsworth Center, USA.
Lindsay TomaszekThe Arbovirus Laboratory, New York State Department of Health, Wadsworth Center, USA.
Jessica StoutThe Arbovirus Laboratory, New York State Department of Health, Wadsworth Center, USA.
Anne F PayneThe Arbovirus Laboratory, New York State Department of Health, Wadsworth Center, USA.
Alan P DupuisThe Arbovirus Laboratory, New York State Department of Health, Wadsworth Center, USA.
Alexander T CiotaThe Arbovirus Laboratory, New York State Department of Health, Wadsworth Center, USA.
Kyle CarsonDiagnostic Immunology Laboratory, New York State Department of Health, Wadsworth Center, USA.
Lindsey A JonesDiagnostic Immunology Laboratory, New York State Department of Health, Wadsworth Center, USA.ORCID https://orcid.org/0000-0002-7989-0418
Kelly HowardDiagnostic Immunology Laboratory, New York State Department of Health, Wadsworth Center, USA.
William T LeeDiagnostic Immunology Laboratory, New York State Department of Health, Wadsworth Center, USA.
Jennifer WhiteBureau of Communicable Disease Control, New York State Department of Health, USA.

Funding

Powassan virus evolution, fitness, and pathogenesis in the Northeast and Midwest United StatesR01AI179758 · NIAID · UNIVERSITY OF MINNESOTA · PI Matthew T Aliota, Alexander Timothy Ciota · 2024 to 2026
$2.1M
CDC HHS U01CK000509NCEZID CDC HHS NU50CK000486NIAID NIH HHS R01 AI179758NIH HHS AI097137,AI142572
6 · The paper itself

Abstract

Powassan virus (POWV), a tick-borne flavivirus, is an emerging public health threat in the United States. In New York State (NYS), incidence of human POWV infection has increased in recent years. We describe the epidemiology of confirmed and probable POWV infection cases reported in NYS from 2013 to 2023. A total of 44 human cases were reported over the study period, with the highest incidence rates in Columbia and Putnam counties. Most cases occurred in White, non-Hispanic males over age 50. Hospitalization was reported in 91% of cases, and 11% were fatal. Human case data and tick surveillance results were analysed to assess spatiotemporal patterns of disease emergence. Spatial analysis revealed clustering of human cases in the Capital and Metropolitan regions of NYS. The prevalence of POWV in adult tick populations increased significantly statewide, and entomological risk was positively but modestly correlated to disease incidence at the ZIP code level. These findings suggest that POWV infection is emerging in geographically concentrated areas of NYS, highlighting the need for enhanced surveillance and targeted prevention efforts in high-risk regions.

Indexed as

Encephalitis, Tick-BorneEncephalitis Viruses, Tick-BorneAdolescentAdultAgedAged, 80 and overAnimalsChildChild, PreschoolFemaleHumansIncidenceInfantMaleMiddle AgedNew YorkepidemiologyIxodes scapularis, Powassan encephalitisPowassan virustick-borne diseases

Identifiers

PMID41623250
PMCPMC12914469

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.