ArticleCurrent medical imaging2026
Utility of Diffusion Weighted Magnetic Resonance Imaging in Early Detection and Staging of Acute Pancreatitis: Correlation with Revised Atlanta Classification
Article in Current medical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundAcute pancreatitis (AP) is associated with a high mortality rate that is directly related to its severity. Limited research has been conducted on the role of DWI-MRI in the diagnosis and staging of acute pancreatitis as it pertains to the revised Atlanta classification. The objective of this study was to examine the role of diffusion-weighted (DW) magnetic resonance imaging (MRI) in early diagnosis and staging of acute pancreatitis in correlation to the revised Atlanta classification.
methodsAccording to the revised Atlanta classification, a prospective assessment was performed to examine the correlation between DW MRI and apparent diffusion coefficient (ADC) values with the severity of acute pancreatitis (AP) in a sample of 34 patients diagnosed with AP.
resultsThe mean ADC value of mild edematous pancreatitis was 1.14±0.06x10-3 mm2/sec, moderate edematous pancreatitis was 1.18±0.16x10-3 mm2/sec, severe necrotizing pancreatitis was 1.99±0.06x10-3 mm2/sec, and that of the normal pancreas was 1.54±0.05 x10-3 mm2/sec. Based on the revised Atlanta classification, there was a significant difference between the ADC values of normal pancreas and acute, severe, and mild/moderate pancreatitis, while there was no significant difference between mild and moderate pancreatitis cases. ROC analysis yielded high accuracy in differentiating normal pancreas from acute pancreatitis and severe pancreatitis from non-severe pancreatitis (AUC=0.827 and 0.870, respectively). DISCUSSION: In the current study, the qualitative assessment of DWI images indicated that all cases of mild acute pancreatitis (AP) displayed true diffusion restriction, while facilitated diffusion was observed in 80% of patients diagnosed with necrotizing pancreatitis. Our findings have validated the outcomes of earlier research regarding the average ADC values of both the healthy and acutely inflamed pancreas. According to the Revised Atlanta Classification, DWI has the ability to assist in the prompt diagnosis of acute pancreatitis and to differentiate mild forms from severe ones.
conclusionDW-MRI using both qualitative and quantitative methods provides a concise, safe, and radiation-free imaging method for early detection and assessing the severity of acute pancreatitis.
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