Evidence map›Paper›PMID 41622997›Full record

ArticleGut microbes2026

A novel exopolysaccharide from

Yue Li, Jialin Wang, Hailing Wang, Xin Ma, Dayong Ren, Binghua Wang

Abstract read
In one paragraph

Article in Gut microbes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Combined Effect ofFoods (Basel, Switzerland) · 2026
    Article
  6. Review
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yue LiCollege of Food Science and Engineering, Jilin Agricultural University, Changchun, China.ORCID 0009-0007-6507-3488
Jialin WangCollege of Food Science and Engineering, Jilin Agricultural University, Changchun, China.
Hailing WangCollege of Food Science and Engineering, Jilin Agricultural University, Changchun, China.
Xin MaState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Dayong RenCollege of Food Science and Engineering, Jilin Agricultural University, Changchun, China.ORCID 0009-0000-3112-3239
Binghua WangDepartment of Central Laboratory, Clinical Laboratory, Jing'an District Central Hospital, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypercholesterolemia is a major risk factor for atherosclerotic cardiovascular disease; however, current therapeutic options such as statins are limited by issues including hepatotoxicity and patient intolerance. Probiotics and their metabolites show promise in modulating cholesterol metabolism through the gut‒liver axis, yet the specific commensal bacteria and molecular mechanisms underlying these effects remain poorly understood. In this study, we isolated and characterized EPS-D1, a novel exopolysaccharide (15.003 kDa) derived from

Indexed as

CholesterolFibroblast Growth FactorsHypercholesterolemiaLactiplantibacillus plantarumPolysaccharides, BacterialReceptors, Cytoplasmic and NuclearAnimalsCholesterol 7-alpha-HydroxylaseGastrointestinal MicrobiomeHumansLiverMaleMiceMice, Inbred C57BLReceptor, Farnesoid X-ActivatedCholesterolCholesterol 7-alpha-Hydroxylasefibroblast growth factor 15, mouseFibroblast Growth FactorsPolysaccharides, BacterialReceptor, Farnesoid X-ActivatedReceptors, Cytoplasmic and Nuclearcholesterol metabolismenterohepatic FXR–FGF15 axisexopolysaccharideLactiplantibacillus plantarum H6Muribaculum

Identifiers

PMID41622997
PMCPMC12867402

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.