Evidence map›Paper›PMID 41622987›Full record

ArticleEuropean journal of neurology2026

Long-Term Survival and Life Expectancy After Spinal Cord Injury in Salzburg, Austria: A Retrospective Population-Based Study.

Mahdi Safdarian, Aljoscha Thomschewski, Stefan Leis, Laura Schnetzer, Georg Zimmermann, Wolfgang Voelckel, Thomas Freude, Eugen Trinka

Abstract read
In one paragraph

Article in European journal of neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mahdi SafdarianDepartment of Neurology, Neurocritical Care and Neurorehabilitation, Christian Doppler University Hospital, Centre of Cognitive Neuroscience, Paracelsus Medical University, Salzburg, Austria.ORCID 0000-0001-7219-9416
Aljoscha ThomschewskiDepartment of Neurology, Neurocritical Care and Neurorehabilitation, Christian Doppler University Hospital, Centre of Cognitive Neuroscience, Paracelsus Medical University, Salzburg, Austria.
Stefan LeisDepartment of Neurology, Neurocritical Care and Neurorehabilitation, Christian Doppler University Hospital, Centre of Cognitive Neuroscience, Paracelsus Medical University, Salzburg, Austria.
Laura SchnetzerVorarlberg Institute for Vascular Investigation and Treatment, Feldkirch, Austria.ORCID 0000-0001-8152-7186
Georg ZimmermannDepartment of Artificial Intelligence and Human Interfaces, Faculty of Digital and Analytical Sciences, Paris Lodron University, Salzburg, Austria.ORCID 0000-0002-8282-1034
Wolfgang VoelckelDepartment of Anesthesiology and Intensive Care Medicine, AUVA Trauma Center Salzburg, Salzburg, Austria.
Thomas FreudeUniversity Hospital for Orthopaedics and Traumatology, Paracelsus Medical University, Salzburg, Austria.
Eugen TrinkaDepartment of Neurology, Neurocritical Care and Neurorehabilitation, Christian Doppler University Hospital, Centre of Cognitive Neuroscience, Paracelsus Medical University, Salzburg, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSpinal cord injury (SCI) is associated with substantial morbidity, premature mortality, and reduced life expectancy. However, population-based survival data that include both traumatic and non-traumatic cases are limited.

methodsWe retrospectively analyzed all 587 Salzburg residents diagnosed with SCI between 2013 and 2023. Cases were identified from hospital records and verified through the Austrian mortality registry. Crude mortality rates (CMRs) at 1-, 2-, and 5-year intervals, standardized mortality ratios (SMRs), and life expectancy (LE) differences compared with the general population were calculated by age, sex, and injury type. Causes of death were classified as natural or external.

resultsOf 587 patients, 488 (83%) had non-traumatic and 99 (17%) traumatic SCI; median age at onset was 62 years. By January 2025, 138 patients (24%) had died, predominantly from cardiovascular and neoplastic causes. CMRs increased steeply with age, rising from 10.5 per 100,000 at 1 year to 19.4 at 5 years. SMRs were markedly elevated in younger patients (e.g., age 30-44: 71.7 at 1 year) and decreased with advancing age. Life expectancy was consistently lower than in the general population, with the greatest reductions in younger and middle-aged males with non-traumatic injuries (e.g., 50-year-old males: LE difference 3.4 years at 1 year).

conclusionsSCI substantially reduces life expectancy, with younger individuals experiencing disproportionate relative mortality and older adults bearing the highest absolute risk. These findings highlight the need for tailored long-term strategies, including preventive measures for younger patients and comprehensive chronic disease management for older populations.

Indexed as

Life ExpectancySpinal Cord InjuriesAdolescentAdultAgedAged, 80 and overAustriaCause of DeathFemaleHumansMaleMiddle AgedRetrospective StudiesYoung Adultcause of deathcrude mortality rateepidemiologylife expectancyspinal cord injurystandardized mortality ratiosurvival

Identifiers

PMID41622987
PMCPMC12862429

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.