Evidence map›Paper›PMID 41622816›Full record

ArticlePublic health nutrition2026

Association between coffee consumption habits and non-alcoholic fatty liver disease in community-dwelling populations: data from the National Health and Nutrition Examination Survey 2013-2018.

Penglin Chen, Shiyan Wang, Tao Zhang, En Qiang Chen

Abstract read
In one paragraph

Article in Public health nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Penglin ChenDepartment of Pharmacy, West China Hospital, Sichuan Universityhttps://ror.org/007mrxy13, Chengdu610041, China.ORCID https://orcid.org/0009-0007-7960-9968
Shiyan WangDepartment of Pharmacy, West China Hospital, Sichuan Universityhttps://ror.org/007mrxy13, Chengdu610041, China.ORCID https://orcid.org/0000-0001-6673-0020
Tao ZhangDepartment of Pharmacy, West China Hospital, Sichuan Universityhttps://ror.org/007mrxy13, Chengdu610041, China.
En Qiang ChenCenter of Infectious Diseases, West China Hospital, Sichuan University, Chengdu610041, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveExisting evidence suggests a potential association between coffee consumption and non-alcoholic fatty liver disease (NAFLD, now known as MASLD), yet the nature of this relationship remains ambiguous. The primary objective of this study was to comprehensively investigate and clarify the association between coffee intake and the occurrence of NAFLD.

designA cross-sectional study design was employed, analysing data from National Health and Nutrition Examination Survey (NHANES) spanning from 2013 to 2018. Weighted univariate and multivariate logistic regression models were utilised to assess the relationship between coffee consumption and NAFLD. Restricted cubic spline analysis was conducted to explore any potential nonlinear associations. Forest plots were generated to visualise the impact of coffee consumption on NAFLD across different subgroups, and threshold effect analysis was performed to evaluate the nonlinear relationship between coffee consumption and NAFLD prevalence specifically in women.

settingData were from the US - representative NHANES.

participants8062 subjects aged ≥ 20 years were included.

resultsThe weighted prevalence of NAFLD among the participants was 44·18 %. After controlling for confounding variables, coffee consumption was found to be negatively associated with the risk of NAFLD (OR = 0·96, 95 % CI: 0·94, 0·99). The association between coffee consumption and NAFLD was observed to vary by gender and education level. For the prevention of NAFLD in women, the optimal coffee intake was determined to be two cups.

conclusionsIncreasing coffee intake emerges as a potentially effective non-pharmacological strategy for the prevention and management of NAFLD. Notably, for women, consuming two cups of coffee appears to represent the optimal threshold for maximising this beneficial effect.

Indexed as

CoffeeNon-alcoholic Fatty Liver DiseaseAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedNutrition SurveysPrevalenceRisk FactorsUnited StatesYoung AdultCoffeeCoffeeCross-sectional studyMetabolic dysfunction-associated steatotic liver disease (MASLD)NHANESNon-alcoholic fatty liver disease (NAFLD)

Identifiers

PMID41622816
PMCPMC12951349

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.