Evidence map›Paper›PMID 41622777›Full record

ArticleFuture science OA2026

Vaginal vitamin D for Genitourinary syndrome of menopause: a cohort study and literature review.

Christopher Massaad, Rawan Abdul Razzak, Kariman Ghazal

Abstract read
In one paragraph

Article in Future science OA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christopher MassaadFaculty of Medicine, Saint George University of Beirut, Beirut, Lebanon.
Rawan Abdul RazzakObstetrics and Gynecology, Lebanese University, Beirut, Lebanon.
Kariman GhazalObstetrics and Gynecology, Lebanese University, Beirut, Lebanon.ORCID 0000-0002-3199-631X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGenitourinary syndrome of menopause (GSM) is a condition resulting from hypoestrogenism, characterized by symptoms such as vaginal dryness, irritation, urinary urgency, and sexual dysfunction. While conventional treatments include local estrogen therapy and non-hormonal alternatives, evidence suggests a therapeutic role for vitamin D. RESEARCH DESIGN AND

methodsThis study assessed the efficacy of vaginal vitamin D supplementation in alleviating GSM symptoms and evaluated clinical factors. Two cohorts were analyzed: 110 postmenopausal women with GSM symptoms and 39 participants aged 35-85 for age-related analysis. Data were analyzed using SPSS Version 26.

resultsFindings revealed associations between age and pelvic exam outcomes, with older women more likely to exhibit atrophic cervix, while younger participants presented with cervicitis. Delivery mode was also significantly correlated with pelvic exam findings (

conclusionsThese support vitamin D as effective non-hormonal GSM therapy, pending larger RCTs.

Indexed as

cervicitisGenitourinary syndrome of menopausemenopausal symptomsnon-hormonal therapypelvic examinationpostmenopausal womenvaginal healthvaginal vitamin D

Identifiers

PMID41622777
PMCPMC12867353

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.