ArticleMagnetic resonance in medicine2026
Effects and Correction of Patient Bulk Motion in Cranial DENSE MRI.
Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
purposeApplications of DENSE to measure cardiac driven brain tissue pulsations are highly sensitive to bulk patient motion due to the sub-millimeter displacement encoding required, limiting its accuracy, reproducibility, and use in pediatric and aging populations. This study aims to assess the impact of induced bulk motion on DENSE scans and to what extent these motion effects can be mitigated with existing and newly proposed methods.
methodsParticipants (N = 10) underwent test-retest 2D DENSE scans at three slice locations with and without induced motion using a 3.0 T system. Brain displacement fields were calculated using pipelines without and with motion correction based on polynomial fitting to an outer ring of brain tissue. Subsequently, voxel-wise comparisons were made between scans and pipelines to evaluate scan repeatability and measure biases in displacement measures.
resultsIn comparing scans with and without induced motion, motion significantly impacted displacement measures, resulting in intensity variations and phase wrap artifacts, as well as increased the mean peak-to-peak displacements. Motion-correction removed the intensity variations and phase wrap observed in phase images, and reduced variations between scans taken with and without induced motion (
conclusionMotion correction significantly improved the correspondence of DENSE measures acquired during induced motion and improved test-retest reproducibility, even in the absence of induced motion.
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