Evidence map›Paper›PMID 41622677›Full record

ArticleBiophysical journal2026

The Lassa virus fusion domain has structural plasticity and exploits bis(monoacylglycero)phosphate for fusion.

Hallie N Pennington, Kiruthika Prahadeesh, Quinn M Mulvihill, Sungjai Shin, Wonpil Im, Jinwoo Lee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biophysical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hallie N PenningtonDepartment of Chemistry and Biochemistry, College of Computer, Mathematics, and Natural Science, University of Maryland, College Park, Maryland.
Kiruthika PrahadeeshDepartment of Chemistry and Biochemistry, College of Computer, Mathematics, and Natural Science, University of Maryland, College Park, Maryland.
Quinn M MulvihillDepartment of Chemistry and Biochemistry, College of Computer, Mathematics, and Natural Science, University of Maryland, College Park, Maryland.
Sungjai ShinDepartment of Chemistry and Biochemistry, College of Computer, Mathematics, and Natural Science, University of Maryland, College Park, Maryland.
Wonpil ImDepartment of Biological Sciences, College of Arts and Sciences, Lehigh University, Bethlehem, Pennsylvania.
Jinwoo LeeDepartment of Chemistry and Biochemistry, College of Computer, Mathematics, and Natural Science, University of Maryland, College Park, Maryland. Electronic address: jinwoo@umd.edu.

Funding

Replacement of an outdated 600 MHz NMR CryoProbe systemS10OD030350 · OD · UNIV OF MARYLAND, COLLEGE PARK · PI ZHANG, DAONING · 2021 to 2021
$341k
NIH HHS S10 OD030350
6 · The paper itself

Abstract

Infection with Lassa virus (LASV), an arenavirus endemic to West Africa, results in a viral hemorrhagic fever with high mortality rates and public health implications. The glycoprotein complex is central to LASV's infectivity as it mediates viral entry via membrane fusion. The fusion domain (FD) (G

Indexed as

Lassa virusLysophospholipidsMembrane FusionMonoglyceridesViral Fusion ProteinsVirus InternalizationAmino Acid SequenceAnimalsCell MembraneProtein Domainsbis(monoacylglyceryl)phosphateLysophospholipidsMonoglyceridesViral Fusion Proteins

Identifiers

PMID41622677
PMCPMC13351859

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.