Evidence map›Paper›PMID 41622481›Full record

ArticleNeural regeneration research2026

Semaglutide exerts neuroprotective effects by blocking the interleukin-17/NOD-like receptor family pyrin domain containing 3-mediated neuroinflammation pathway after traumatic brain injury.

Bin Zhang, Lu Kong, Yumei Wang, Wei He, Mengshi Yang, Xueling Zhang, Xiyu Chen, Yaxuan Zhang, Baiyun Liu, Miao Bai and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neural regeneration research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bin ZhangDepartment of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Lu KongDepartment of Neurosurgery, Qingdao Municipal Hospital, Qingdao, Shandong Province, China.
Yumei WangDepartment of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Wei HeDepartment of Neurosurgery, Qilu Hospital of Shandong University (Qingdao), Qingdao, Shandong Province, China.
Mengshi YangDepartment of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Xueling ZhangDepartment of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Xiyu ChenDepartment of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yaxuan ZhangDepartment of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Baiyun LiuDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Miao BaiDepartment of Neurology, The First Hospital of Tsinghua University, Beijing, China.ORCID 0009-0002-0480-5474
Guangzhi ShiDepartment of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.ORCID 0000-0003-4189-5800

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

apoptosisblood–brain barrierbrain edemaglucagon-like peptide-1 receptorinterleukin-17neuroinflammationneuronal survivalsecondary brain injurysemaglutidetraumatic brain injury

Identifiers

PMID41622481
PMCPMC13557656

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.