Evidence map›Paper›PMID 41622316›Full record

ArticleScientific reports2026

Uncovering the potential MTAs, candidate genes and microRNAs regulatory networks involved in salinity stress tolerance triggered in Iranian Aegilops tauschii.

Hossein Sabouri, Niloofar Nikkhah, Borzo Kazerani, Aylin Zebarjad, Hossein Hosseini Moghadam, Maryam Pasandideh Arjmand, Zahra Pezeshkian, Sayed Javad Sajadi

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Hossein SabouriDepartment of Plant Production, College of Agriculture Science and Natural Resource, Gonbad Kavous University, Gonbad Kavous, Iran. hossein.sabouri@gonbad.ac.ir.
Niloofar NikkhahDepartment of Plant Production, College of Agriculture Science and Natural Resource, Gonbad Kavous University, Gonbad Kavous, Iran.
Borzo KazeraniDepartment of Plant Breeding and Biotechnology, Faculty of Plant Production, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran.
Aylin ZebarjadDepartment of Plant Production, College of Agriculture Science and Natural Resource, Gonbad Kavous University, Gonbad Kavous, Iran.
Hossein Hosseini MoghadamDepartment of Plant Production, College of Agriculture Science and Natural Resource, Gonbad Kavous University, Gonbad Kavous, Iran.
Maryam Pasandideh ArjmandDepartment of Plant Biotechnology, Faculty of Agricultural Sciences, University of Guilan, Rasht, Iran.
Zahra PezeshkianDepartment of Animal Sciences, Faculty of Agricultural Sciences, University of Guilan and National Inland Water Aquaculture Institute, Rasht, Iran.
Sayed Javad SajadiDepartment of Plant Production, College of Agriculture Science and Natural Resource, Gonbad Kavous University, Gonbad Kavous, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the molecular diversity and identified marker-trait associations (MTAs), candidate genes, and microRNAs (miRNAs) regulatory networks in Iranian Aegilops tauschii ecotypes under salinity stress during the seedling stage. The results demonstrated that ISJ9 exhibited the highest values for polymorphic information content (PIC), effective number of alleles (Ne), gene diversity (h), Shannon's information index (I). Similarly, OPE03-Xgwm44-7DF displayed the highest Ne and I values. Therefore, ISJ9 and OPE03-Xgwm44-7DF markers demonstrated the greatest discriminatory power for distinguishing Aegilops tauschii ecotypes. Association analysis under salinity stress identified 115 MTAs, including iPBS44-D and OPB01-Xgwm44-7DR-3. Subsequent bioinformatics analyses revealed 254 candidate genes and 107 regulatory microRNAs associated with salinity tolerance. Several important candidate genes and their regulatory miRNAs identified in this study function significantly in salinity stress response. Gene ontology analysis determined the most significant biological processes, cellular components, and molecular functions, while pathway analysis revealed genes involved in glutathione metabolism pathways. Protein-protein interaction networks indicated that interacting genes were physically or functionally related. The identified candidate genes and miRNAs provide valuable resources for breeding programs, including marker-assisted selection (MAS) and genome editing, to develop salinity stress-tolerant wheat varieties.

Indexed as

AegilopsGene Regulatory NetworksMicroRNAsSalt StressSalt ToleranceComputational BiologyGene Expression Regulation, PlantIranMicroRNAsAgilops tauschiiAssociation analysisCandidate genesMicroRNAs regulatory networksProtein–protein interactionSalinity stress

Identifiers

PMID41622316
PMCPMC12916928

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